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In this issue: Statins and liver function; dosing timing for thyroxine; rivaroxaban for VTE, DVT, and stroke; echinacea and the common cold; and FDA actions.
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As reported here in 2003, the World Bank began funding a project to train giant pouched Gambian rats to sniff out tuberculosis (TB) in sputum specimens in sub-Saharan Africa. Rats have been successfully trained to target landmines, and using a similar training/reward technique, pilot data suggested that rats could be trained to detect TB in respiratory specimens.
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Two cases were reported in this paper. the first case was a 52-year-old wildlife biologist who went deer hunting in Virginia in November 2008.
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Group B streptococcal (GBS) disease is the leading cause of early-onset neonatal sepsis (within the first week of life) in the United States.
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In this study, 2,499 hiv-seronegative men or transgender females who have sex with men (MSM) were randomized to daily TDF/FTC vs. placebo in a multicenter, controlled trial with clinical sites in North America, Latin America, Thailand, and Africa.
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I was asked earlier this week to see a patient with candidemia. The patient had severe cirrhosis and had previously had placement of a transjugular intrahepatic portosystemic shunt (TIPS) for control of complications of portal hypertension.
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In 1854, london was rocked by a cholera epidemic that killed approximately 10,000 people. Using what are now considered classical epidemiological methods, Dr. John Snow traced the source of at least 500 of the infections to a single water pump at Broad Street, validating his theory that cholera was a water-borne disease 29 years before the etiologic agent was discovered by Robert Koch; removing the pump handle stopped the outbreak in that area.
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In this issue: Rivaroxaban may be dabigatran's first competitor; a new way to measure non-adherence to medication therapy; FDA Actions.
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These authors examined the use of antimicrobials for skin and soft tissue infection (SSTI), comparing the presentation, complications, microbial results and outcomes of adults hospitalized at Denver Health Medical Center.