Viral Infections
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Infectious Disease Updates
COVID Monoclonals Needed for PrEP; Oral Camostat Ineffective in COVID-19; Mpox: Lessons Learned from Rio
Death Due to the ‘No Name’ Virus in Santa Fe
There is no specific treatment for hantavirus infection and no vaccine. Prevention consists of control and avoidance of rodents and their body fluids and excreta.
Measles Vaccination in Adults in 2025
The Centers for Disease Control and Prevention has updated measles vaccination recommendations.
RSV Vaccination in Severely Immunocompromised Individuals
The antibody response to respiratory syncytial virus vaccination is significantly impaired in many severely immunocompromised individuals.
Oseltamivir for Adults Hospitalized with Influenza: Earlier Is Better
A multicenter observational study on adults hospitalized with influenza found that initiation of oseltamivir on the day of admission reduced the risk of disease progression, including pulmonary and extra-pulmonary organ failure and death.
Parvovirus and Increasing Danger in Pregnancy and Sickle Cell Disease
The incidence of human parvovirus B19 infection is increasing in the United States, putting vulnerable groups at risk of serious complications.
Effectiveness of Nirmatrelvir-Ritonavir in Hospitalized Patients with COVID-19
A study that compared nirmatrelvir-ritonavir, remdesivir, or a combination of both for hospitalized patients with COVID-19 found those who received nirmatrelvir-ritonavir monotherapy had lower mortality, reduced intensive care unit admission, and reduced need for mechanical ventilation.
Metformin Reduces SARS-CoV-2 Viral Load in Outpatients with COVID-19
A randomized, placebo-controlled clinical trial of outpatients with COVID-19 found that metformin reduced SARS-CoV-2 viral load 3.6-fold compared to placebo, while ivermectin and fluvoxamine showed no benefit.
A Review of Throat Infections: Low-Acuity Disease
Sore throats are common pediatric chief complaints, with etiologies ranging from thrush to epiglottitis. All clinicians must be familiar with the diversity of causes from benign to life-threatening in order to decrease morbidity and mortality with a timely diagnosis.
Outbreak of Marburg Virus Disease in Rwanda
A rising number of cases of Marburg virus disease, which is caused by one of the most virulent human pathogens, have been reported in Rwanda. Marburg virus infections in humans are rare but can present with a rapidly progressive febrile illness that can lead to multi-organ failure and shock with case-fatality rates of up to 80% to 90%.