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Care of the critically ill pregnant patient poses unique challenges. The normal physiology of a pregnant patient differs considerably from that of a non-pregnant patient and these differences may affect many aspects of routine care: resuscitation, mechanical ventilation, choice of drugs and use of diagnostic studies are some examples.
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This observational study from a university-affiliated, urban, tertiary hospital in Toledo, OH, retrospectively reviewed the records of 840 patients admitted to various ICUs to determine if the time to first visit by a physician had an effect on a number of clinically relevant outcomes.
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The purpose of this meta-analysis was to assess the efficacy of subglottic secretion drainage in preventing ventilator-associated pneumonia (VAP). Dezfulian and colleagues performed a comprehensive analysis of randomized trials that have compared subglottic secretion drainage with a standard endotracheal tube care in mechanically ventilated patients.
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In the absence of definitive systematic reviews, and in the presence of evidence for continued widespread administration of low-dose dopamine infusions to critically ill patients for the purpose of preventing renal failure, Friedrich and colleagues performed an exhaustive review of the literature on this subject.
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Rachmale and colleagues retrospectively identified 210 patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS) undergoing mechanical ventilation for longer than 48 hours.
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Using a statewide administrative database and other sources, Gershengorn and colleagues examined data on all adult patients with a primary diagnosis of diabetic ketoacidosis (DKA) who were admitted to hospitals in the state of New York from 2005-2007.
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In this issue: Side effects of finasteride; new ruling on pharmaceutical companies paying generic manufacturers; and FDA actions.
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This blinded, randomized, multicenter trial compared the colloid solution low-molecular-weight hydroxyethyl starch (HES 130/0.42) with the crystalloid solution Ringer's acetate for the treatment of severe sepsis.
