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Neuropsychological Assessment Reduces False Positives in Mild Cognitive Impairment
Synopsis: Traditional comprehensive neuropsychological testing has greater reliability, sensitivity, and specificity than bedside screening tests in the accurate diagnosis of mild cognitive impairment. -
Role of Neurologists and Diagnostic Tests in the Management of DSP
Synopsis: Using the clinical history and simple, inexpensive laboratory tests, community-based outpatient neurologists were able to determine the cause of distal symmetric polyneuropathy in three-fourths of patients presenting with typical symptoms. -
Chemotherapy-Induced Neuropathy in Pediatrics
Synopsis: Chemotherapy-induced peripheral neuropathy is common in children treated for a variety of cancers, but the long-term prognosis for recovery is excellent. -
To Sleep, Perchance to Clear Our Beta-Amyloid
SYNOPSIS: Both animal studies and human data suggest that A-beta 42 amyloid is cleared from the brain during sleep, and that sleep deprivation may be a risk factor for the development of Alzheimer’s disease.
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New Diagnostic Methods for Creutzfeldt-Jakob Disease
Synopsis: Novel noninvasive diagnostic tests for Creutzfeldt-Jakob disease (CJD; nasal brushings) and variant CJD (urinary prion proteins) are reported to be highly sensitive and specific in two recent studies.
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Treatment of Sexually Transmitted Disease: Update 2002
This report updates the CDCs previous edition of this resource, the 1998 Guidelines for Treatment of Sexually Transmitted Diseases. The recommendations were formulated through a multi-stage process that included a three-day meeting in Atlanta in September 2000, when consultants reviewed the literature and debated the evidence. While the guidelines emphasize treatment, diagnostic and prevention strategies also are discussed. -
Practice Guideline Authors’ Ties to Pharmaceutical Industry Not Always Clear
During the last several years, the relationship between physicians and the pharmaceutical industry has come under increasing scrutiny. However, no literature has been published examining potential financial conflicts of interest for authors of commonly used clinical practice guidelines (CPGs). This cross-sectional study from Toronto surveyed 192 authors of 44 CPGs on common diseases endorsed by North American and European specialty societies. -
ECG Review: ST Elevation in Lead aVL
The 12-lead ECG shown in the Figure was obtained from a 50-year-old man with new-onset chest pain. In view of a negative prior history of coronary disease, what might cardiac catheterization show? -
Ultrasound Guidance Offers Visual Help for Placement of Central Venous Catheters
Ultrasound guidance (USG) for the placement of central venous catheters (CVC) has been recognized as a helpful adjunct in anesthesia and surgical literature since 1984, but has received little notice in the emergency medicine (EM) literature. To clarify the EM role of this emerging technique, Miller and colleagues compared USG to the traditional landmark technique for insertion of CVC in ED patients without obtainable peripheral access. -
Special Feature: The Electrocardiogram in Wellens’ Syndrome
Among the many electrocardiographic findings indicative of acute coronary syndromes, the emergency physician must be familiar with the characteristics of the pre-infarction stage of coronary artery disease known as Wellens syndrome.