Stroke
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These Suits Against EPs Became Indefensible: Medical Records Were Altered
In a case related to the alleged delay in providing care to a patient, an emergency physician (EP) was accused of altering the time that he ordered certain treatments for the patient. -
Side Effects of Opioids
More than 40% of ED visits are related to pain.1 The Joint Commission has made the assessment and treatment of pain in the ED one of its standards.2 The use of opioid medications has been increasing in both adults and children.3-5 In 2009 there were more than 200 million prescriptions for opioid medications, with enough medication dispensed to supply every adult in the United States with the equivalent of 5 mg of hydrocodone every four hours for one month.
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Stroke Alert
Carotid MRI scanning was performed in 1414 stroke-free participants, older than the age of 45 years, to assess the morphology of any atherosclerotic plaques, specifically to look at the presence of a lipid core, intraplaque hemorrhage, calcification, or fibrous tissue in each carotid artery. -
Anti-Titin Antibodies in Myasthenia Gravis
In addition to autoantibodies directed against the acetylcholine receptor (AchR) and the receptor-associated protein muscle-specific tyrosine kinase (MuSK) patients with myasthenia gravis (MG) demonstrate a host of other antibodies. -
Hypoperfusion Response During Cortical Spreading Depolariz
This study examines and describes the occurrence of an inverse neurovascular coupling response in peri-contusional brain tissue as a potential and novel mechanism for secondary brain injury. -
The Photosensitive Patient
A 65-year-old female presents to the emergency department with a chief complaint of a severe rash. The rash has been present for two weeks on her arms, neck, and scalp. It began while she was sitting on her porch one afternoon. She denies any associated fevers, chills, headache, or muscle ache. She denies any exposure to pets, new soaps, detergents, or lotions, and she denies recent travel.
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Intravenous Calcitonin Gene-Related Antibodies for the Prevention of Migraine
In a Phase 2 trial, antibodies to calcitonin gene-related peptide resulted in a significant decrease in migraine days measured from baseline to weeks 5 to 8 after one intravenous infusion of the medication, as compared to a placebo infusion. But the high-rate of placebo response (50%) warrants caution in the interpretation of the study results and requires more investigation. -
Utility of Anti-JC Virus Antibody Index to Assess the Risk of PML in Natalizumab-Treated MS Patients
Natalizumab is a monoclonal antibody that is FDA-approved for the treatment of relapsing-remitting multiple sclerosis (MS). Among the available options to treat MS, it is one of the most effective. -
DaTSCAN to Distinguish Parkinson’s Disease from Secondary Parkinsonism
DaTSCAN imaging makes use of the dopamine transporter (DAT) ligand [123I]FP-CIT used with SPECT to provide a means to visualize the integrity of the nigrostriatal dopaminergic system. DaTSCAN has been approved in the United States to aid in evaluation of patients in whom Parkinsons disease (PD) and certain other related neurodegenerative disorders are suspected. -
Pediatric Myocarditis
Myocarditis can at times be asymptomatic and has a varied presentation; consequentially, it often goes undiagnosed and its true incidence is unknown