Stroke
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Incidental Cerebral Microbleeds and Cerebral Blood Flow in Elderly Individuals
Cerebral microbleeds in non-demented elderly people are associated with a global reduction in cerebral blood flow and a high prevalence of beta-amyloid deposition in the brain.
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Idarucizumab: A Promising New Drug that Reverses the Anticoagulant Effects of Dabigatran
A recent study found that idarucizumab rapidly reverses the effects of dabigatran and is likely to have important clinical benefits for patients with intracerebral hemorrhage and other disease processes in which reversal of anticoagulation is important.
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Convexal Subarachnoid Hemorrhage and Amyloid Angiopathy
Cerebral amyloid angiopathy is emerging as a major cause of spontaneous intracerebral hemorrhage in the elderly. The authors of this study undertook a careful review of all of the patients in their database over a 9-year period who had spontaneous convexal subarachnoid hemorrhage, and they performed a careful longitudinal analysis of clinical and neuroimaging data.
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Consequences of Intracerebral Hemorrhage in Young Adults
Intracerebral hemorrhage accounts for 10-20% of all strokes in North America and Europe, with an overall incidence of 25 cases per 100,000 population annually. In this study, the authors evaluated the long-term survival and recovery of 268 1-month survivors ages 16-49 years to assess the prognosis of intracerebral hemorrhage in the younger group.
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Natriuretic Peptide Measurements May Help Diagnose Cardioembolic Stroke
The accurate diagnosis of cardioembolic stroke is extremely important since secondary prevention for this disorder, with antithrombotic therapy, is different than for other patients who might be treated with antiplatelet therapy. -
Cryptogenic Stroke and Atrial Fibrillation
In large prospective databases of ischemic stroke, cryptogenic stroke occurs in as many as 30% of all ischemic stroke patients. -
Endovascular Intracranial Clot Extraction Benefits Are Confirmed in Two More Clinical Trials
On April 17, 2015, the New England Journal of Medicine published the results of two randomized clinical trials of endovascular stent-retriever clot extraction for ischemic stroke, simultaneous with their presentation at the European Stroke Conference. These two studies, added to those presented and published at the International Stroke Conference in February, bring the total number of studies to five that have shown dramatic benefits of this therapy in appropriately selected patients with acute ischemic stroke.
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Intracranial Clot Extraction Results in Better Outcomes than Intravenous Thrombolysis Alone
This article will discuss three studies that have been recently published in the New England Journal of Medicine — MR CLEAN, ESCAPE, and EXTEND — regarding intracranial clot extraction for acute ischemic stroke
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Report from the International Stroke Conference 2015
Major announcements at the International Stroke Conference 2015 in Nashville, Tennessee, included reports on three trials that compared endovascular clot retrieval for acute ischemic stroke, compared to medical treatment with intravenous thrombolytics alone. -
Penetrating Thoracic Trauma
Trauma continues to be a significant cause of morbidity and mortality. Accidental death remained the fifth most common cause of death for all ages in 2009. Thoracic injuries reportedly have been involved in up to 75% of all deaths related to trauma and may be directly responsible in up to 25% of these deaths.