Stroke
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Carotid Occlusion Rarely Develops from Asymptomatic Carotid Artery Stenosis
The risk of progression to carotid occlusion is well below the risk of carotid stenting or carotid endarterectomy, and intensive medical therapy appears to be preferred for the vast majority of patients with asymptomatic carotid artery stenosis.
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Every 5-minute Delay in Performing Endovascular Reperfusion Results in 1 out of 100 Patients Having a Worse Disability Outcome
Every 5-minute delay in performing endovascular reperfusion results in 1 out of 100 patients having a worse disability outcome.
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Pediatric Stroke
MONOGRAPH: Pediatric stroke presents a diagnostic challenge to the emergency physician. Here is what to look for and how to best proceed.
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Rate and Predictors of Futile Hospital Transfers for Acute Stroke Endovascular Therapy
A large number of futile transfers take place for consideration of endovascular therapy, and better selection criteria need to be developed.
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Circadian Rhythms Predict Small Vessel Ischemic Disease
The presence of white matter infarcts and cerebral microbleeds is associated with disruption of sleep but not total sleep time.
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Pattern of Atrial Fibrillation Is Associated with Outcomes After Stroke
In a Japanese stroke registry, permanent as opposed to paroxysmal atrial fibrillation was associated with higher in-hospital mortality after stroke.
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Blood Pressure Lowering After Acute Stroke: Can It Kill You?
Patients with chronically elevated blood pressure are at increased risk of all-cause and cardiovascular death, with a particularly increased risk of ischemic and hemorrhagic stroke. Treatment to lower systolic BP decreases stroke risk, without an apparent lower threshold down to 120 mmHg. However, lowered SBP (≤ 120 mmHg) in the 5 years after a stroke may be associated with increased mortality. Lower SBP over a shorter period of time after a stroke in chronically hypertensive patients could potentially increase mortality as well.
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Incidental Cerebral Microbleeds and Cerebral Blood Flow in Elderly Individuals
Cerebral microbleeds in non-demented elderly people are associated with a global reduction in cerebral blood flow and a high prevalence of beta-amyloid deposition in the brain.
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Idarucizumab: A Promising New Drug that Reverses the Anticoagulant Effects of Dabigatran
A recent study found that idarucizumab rapidly reverses the effects of dabigatran and is likely to have important clinical benefits for patients with intracerebral hemorrhage and other disease processes in which reversal of anticoagulation is important.
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Convexal Subarachnoid Hemorrhage and Amyloid Angiopathy
Cerebral amyloid angiopathy is emerging as a major cause of spontaneous intracerebral hemorrhage in the elderly. The authors of this study undertook a careful review of all of the patients in their database over a 9-year period who had spontaneous convexal subarachnoid hemorrhage, and they performed a careful longitudinal analysis of clinical and neuroimaging data.