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Excess Deaths During COVID-19
Compared with death data for the same weeks from prior years, nearly 300,000 excess deaths occurred in the United States between the weeks ending Jan. 26 through Oct. 3, 2020. Two-thirds were attributed to COVID-19.
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Cognitive Benefit of Rivastigmine in Parkinson’s Disease Dementia with Orthostatic Hypotension
Individuals with Parkinson’s disease dementia and orthostatic hypotension (OH) showed more robust cognitive improvement from rivastigmine vs. those without OH. The anti-OH effect of rivastigmine probably mediates this better response.
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How to Record Reliable Blood Pressure Measurements
A small, community-based study to detect hypertension revealed one week of twice-daily home blood pressure (BP) measurements are more reliable and more accurately predict increased left ventricular mass than clinic or 24-hour ambulatory BP monitoring.
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Prior Metformin Use in Patients with Diabetes Hospitalized for COVID-19
Investigators found metformin use before COVID-19 hospitalization for patients with diabetes was associated with a lower risk of death.
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Elderly Patients with Esophageal Cancers Might Tolerate Multimodal Therapy Well
Some clinicians shy away from complete therapy courses for these patients over concerns about frailty, quality of life.
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New Risk Factors for Atherosclerosis
An analysis of the Women’s Health Study based on a recent questionnaire about adverse pregnancy outcomes showed hypertensive disorders of pregnancy and low birth weight are independent predictors of subsequent atherosclerotic cardiovascular disease.
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Can Antioxidant Intake Prevent Coronary Artery Disease?
A study of single nucleotide polymorphisms (SNP) that increase blood levels of diet-derived antioxidants in three large individual subject genetic databases did not demonstrate a relationship between SNPs and coronary artery disease.
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Are Beta-Blockers Still Relevant After a Myocardial Infarction?
A large, contemporary, nationwide, observational study of post-myocardial infarction beta-blocker administration shows that after three months, there were no beneficial effects on adverse cardiovascular events to continued beta-blocker use.
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Statins and Muscle Symptoms: Cause and Effect?
An analysis of three large simvastatin trials revealed muscle symptoms on simvastatin are common, but true myopathy is rare and can be predicted by evaluating certain risk factors for its development, which can help guide patient management.
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Is Effective Transcatheter Tricuspid Repair Becoming a Reality?
In two trials of transcatheter devices treating tricuspid regurgitation, the authors observed high efficacy and low adverse event rates.