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Pesticides and Development of Alzheimer’s Disease — New Evidence
A new case-control study finds that increased levels of dichlorodiphenyldichloroethylene (DDE), which is the metabolite of the pesticide dichlorodiphenyltrichloroethane (DDT), are associated with an increased risk for Alzheimer's disease. -
Trochlear Headache: A Rare, Specific 'Eye-strain' Headache
Trochlear headaches should be considered in patients with new onset, constant, unilateral eye pain, especially when the pain is aggravated by eye movement. -
Neuropathy with Hepatitis C Virus-Related Cryoglobulinemia
Most patients who develop cryoglobulinemia associated with hepatitis C infection will develop symptoms and signs of a symmetric, distal sensory neuropathy. -
The Course of Headache in Idiopathic Intracranial Hypertension
In a prospective study of 35 patients with newly diagnosed idiopathic intracranial hypertension confirmed by diagnostic lumbar puncture and treated with standard medication regimens, 43% of patients had excellent headache outcome at 12 months, with the major improvement seen within the first month of diagnosis. -
Is Exercise Harmful in Charcot-Marie-Tooth Disease?
Unlike other neuromuscular disorders, physical exercise does not appear to worsen weakness in patients with Charcot-Marie-Tooth disease. -
Stroke Alert
At least 30% of strokes in China are caused by intracerebral hemorrhage, compared with approximately 10-15% in North America. -
Somatic Mutations in Cerebral Cortical Malformations
Targeted high-coverage sequencing for causal somatic mutations in patients with cortical malformations is more sensitive than traditional Sanger and whole-exome sequencing. -
Varicella-Zoster Virus and Fingolimod: Much Ado about Not Much?
The risk of varicella-zoster virus infections in patients treated with fingolimod is slightly higher than placebo, but is overall quite low. -
Cerebrospinal Fluid ß-Amyloid 42 vs Amyloid PET Imaging in the Diagnosis of Alzheimer’s Disease
Aß 42, measured in cerebrospinal fluid, may help determine whether patients have normal or increased cortical Aß deposition. Additionally, abnormal PET 18F-flutemetamol retention levels correlate with disease stage in patients with mild cognitive symptoms.