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Two studies have identified a novel inclusion found in a subset of FTLD brains and categorize the clinical entity of the behavioral variant of FTLD, based on anatomical patterns.
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Glatiramer acetate significantly delayed the onset of clinically definite multiple sclerosis (MS) in patients having a clinically isolated event and brain lesions consistent with MS.
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Dementia in Parkinson's disease is associated with a non-tremor-predominant phenotype, and the MAPT H1/H1 genotype. A rapidly progressing subtype without dementia has been identified, associated with another non-motor feature, depression.
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Results from a Phase 3 study of dabigatran, intensive lipid-lowering in CVD, H1N1 vaccine dosing and efficacy, and FDA Actions.
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Oculopharyngeal muscular dystrophy is a rare, autosomal dominant neuromuscular disorder that has recently been genetically defined and may be treatable with myoblast transplantation.
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Hemicraniectomy in Older Patients with Large Middle Cerebral Artery Infarcts Reduces Mortality
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This well-designed, randomized, controlled trial, which included a sham arm, showed no evidence for the efficacy of hyperbaric oxygen therapy to treat the symptomatic, cognitive, and behavioral sequelae of postconcussion syndrome in soldiers after combat-related mild traumatic brain injury.
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Chronic use of sleeping medications, particularly benzodiazepines, is associated with an increase in all-cause mortality, and should be avoided if at all possible.
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A Phase 2 trial of atacicept, a humanized recombinant protein that suppresses B cell function, demonstrated a negative impact on clinical disease activity in relapsing-remitting multiple sclerosis.