Two studies have identified a novel inclusion found in a subset of FTLD brains and categorize the clinical entity of the behavioral variant of FTLD, based on anatomical patterns.
Glatiramer acetate significantly delayed the onset of clinically definite multiple sclerosis (MS) in patients having a clinically isolated event and brain lesions consistent with MS.
Dementia in Parkinson's disease is associated with a non-tremor-predominant phenotype, and the MAPT H1/H1 genotype. A rapidly progressing subtype without dementia has been identified, associated with another non-motor feature, depression.
Results from a Phase 3 study of dabigatran, intensive lipid-lowering in CVD, H1N1 vaccine dosing and efficacy, and FDA Actions.
Oculopharyngeal muscular dystrophy is a rare, autosomal dominant neuromuscular disorder that has recently been genetically defined and may be treatable with myoblast transplantation.
Hemicraniectomy in Older Patients with Large Middle Cerebral Artery Infarcts Reduces Mortality
This well-designed, randomized, controlled trial, which included a sham arm, showed no evidence for the efficacy of hyperbaric oxygen therapy to treat the symptomatic, cognitive, and behavioral sequelae of postconcussion syndrome in soldiers after combat-related mild traumatic brain injury.
Chronic use of sleeping medications, particularly benzodiazepines, is associated with an increase in all-cause mortality, and should be avoided if at all possible.
A Phase 2 trial of atacicept, a humanized recombinant protein that suppresses B cell function, demonstrated a negative impact on clinical disease activity in relapsing-remitting multiple sclerosis.
