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This study validated that anti-aquaporin-4 antibodies are highly specific (99.8%) for Devic's disease and related disorders when tested in a large series of miscellaneous autoimmune and non-autoimmune systemic diseases.
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Small fiber neuropathy (SFN) is a relatively common disorder that affects small somatic and/or autonomic nerves. Known causes include diabetes, vitamin B12 deficiency, and Sjogren's syndrome among others, although the condition is idiopathic in most cases.
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Detailed neuropathological investigation of patients with sensory neuronopathy and polymerase γ mutations revealed evidence of posterior column atrophy in spinal cord sections and marked neuronal cell loss with severe mitochondrial biochemical abnormalities (involving respiratory chain complexes I and IV) in the dorsal root ganglia.
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New treatment for prostate cancer; avastin and breast cancer; new CMS disclosure rule; and FDA actions.
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Exposure to specific solvents, and trichloroethylene in particular, is associated with an increased risk of Parkinson's disease.
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In a carefully studied group of patients who underwent brain biopsies for atypical presentations of multiple sclerosis, cortical demyelination or cortical inflammatory lesions were demonstrated in about half.
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Neurological disease affecting the non-dominant frontal lobe has been associated with a syndrome of "delusional jealousy," referred to as Othello syndrome.
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This clinical study evaluated patients with posterior reversible encephalopathy syndrome to determine the kind of seizures they experienced, abnormalities on EEG, and to correlate this with findings on neuroimaging (MRI).
