This study validated that anti-aquaporin-4 antibodies are highly specific (99.8%) for Devic's disease and related disorders when tested in a large series of miscellaneous autoimmune and non-autoimmune systemic diseases.
Small fiber neuropathy (SFN) is a relatively common disorder that affects small somatic and/or autonomic nerves. Known causes include diabetes, vitamin B12 deficiency, and Sjogren's syndrome among others, although the condition is idiopathic in most cases.
Detailed neuropathological investigation of patients with sensory neuronopathy and polymerase γ mutations revealed evidence of posterior column atrophy in spinal cord sections and marked neuronal cell loss with severe mitochondrial biochemical abnormalities (involving respiratory chain complexes I and IV) in the dorsal root ganglia.
New treatment for prostate cancer; avastin and breast cancer; new CMS disclosure rule; and FDA actions.
Exposure to specific solvents, and trichloroethylene in particular, is associated with an increased risk of Parkinson's disease.
In a carefully studied group of patients who underwent brain biopsies for atypical presentations of multiple sclerosis, cortical demyelination or cortical inflammatory lesions were demonstrated in about half.
Neurological disease affecting the non-dominant frontal lobe has been associated with a syndrome of "delusional jealousy," referred to as Othello syndrome.
This clinical study evaluated patients with posterior reversible encephalopathy syndrome to determine the kind of seizures they experienced, abnormalities on EEG, and to correlate this with findings on neuroimaging (MRI).
