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Intravenous erythropoietin therapy appears to reduce retina nerve fiber layer thinning 16 weeks after onset of optic neuritis, but larger studies needed to detect differences in visual outcome.
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Biomarkers in the cerebrospinal fluid open the possibility of diagnosing early or even presymptomatic cases of Alzheimer's disease, thereby expanding the potential window for therapy.
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This case series of patients with painful legs and moving toes is the largest to date and describes association with female gender, peripheral neuropathy and radiculopathy, cancer, and autoimmune disorders. Neurophysiology suggests an additional central component, supporting recruitment of a spinal cord or brainstem generator.
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Side effects of statins; effects of cannabis use; antihypertensives and lip cancer; and FDA actions.
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In this well-designed, randomized, placebo-controlled clinical trial of antioxidant supplements for Alzheimer's disease, there was no benefit, and some agents were associated with worse outcome.
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An alternate-day steroid protocol appears to be just as efficacious as every-day steroids over the long term in a group of patients with undifferentiated polymyositis, with less serious long-term side effects.
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Multimodal brain imaging demonstrates extensive frontostriatal dysfunction in mild cognitive impairment in early Parkinson's disease.
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Side effects of finasteride; new ruling on pharmaceutical companies paying generic manufacturers; and FDA actions.
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In this long-term, population-based patient series, the authors explore the natural course of drug-resistant epilepsy and explore whether remission can be predicted by clinical features.
