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The diagnosis of limbic encephalitis should be considered in patients who present with progressive memory deficits, confusion, and seizures, as it is a treatable entity in many cases and may suggest the presence of an underlying malignancy.
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Based on a retrospective analysis of 187 patients with neuromyelitis optica (NMO) or an NMO spectrum disorder from three medical centers, the authors report their initial findings on the epidemiology of NMO/NMO spectrum disorders.
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Meningioma surgery can be performed with good results in the elderly, but with increased complications and mortality.
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Lorcaserin for weight loss; statins and fatigue; treatment-resistant gonorrhea; hydrocodone classification changes; USPSTF recommendations; and FDA actions.
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Clinical examination severity appears to be the best predictor of response to immunotherapy in patients with myasthenia gravis.
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Primary progressive apraxia of speech has been well characterized as a distinct neurodegenerative disease, but underlying pathology and prognosis are uncertain in most cases.
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Over a 6-year period, 2305 patients with reduced left ventricular ejection fraction and normal sinus rhythm were randomized to warfarin treatment (target INR of 2.0 to 3.5) or aspirin (325 mg per day) and followed to determine the rate of a composite endpoint of ischemic stroke, intracerebral hemorrhage, or death from any cause.
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Changes in CSF metabolites reflect dopamine and norepinephrine deficiency in Parkinson's disease, and may be sensitive in early identification.
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Azithromycin and cardiac risk; warfarin and heart failure; aspirin and VTE; effectiveness of long-acting contraceptives; and FDA actions.
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Normal pressure hydrocephalus remains a clinical diagnosis and standardized clinical assessments predict a positive response to shunting in most patients.