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The monoclonal antibody alemtuzumab, that targets the CD52 receptor on lymphocytes, reduced acute exacerbations and early disability by 70%.
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The use of sustained pulsed dosing of intravenous immunoglobulin (IVIG) may be useful for treating multiple sclerosis (MS) patients with corticosteroid refractory optic neuritis.
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Excessive use of denture cream, which contains high concentrations of zinc, may cause copper deficiency nervous system syndromes.
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Generalized autonomic failure (GAF) in the presence of a sensory neuropathy strongly suggests amyloidosis.
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This study examines and describes the occurrence of an inverse neurovascular coupling response in peri-contusional brain tissue as a potential and novel mechanism for secondary brain injury.
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In addition to autoantibodies directed against the acetylcholine receptor (AchR) and the receptor-associated protein muscle-specific tyrosine kinase (MuSK) patients with myasthenia gravis (MG) demonstrate a host of other antibodies.
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Carotid MRI scanning was performed in 1414 stroke-free participants, older than the age of 45 years, to assess the morphology of any atherosclerotic plaques, specifically to look at the presence of a lipid core, intraplaque hemorrhage, calcification, or fibrous tissue in each carotid artery.
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DaTSCAN imaging makes use of the dopamine transporter (DAT) ligand [123I]FP-CIT used with SPECT to provide a means to visualize the integrity of the nigrostriatal dopaminergic system. DaTSCAN has been approved in the United States to aid in evaluation of patients in whom Parkinsons disease (PD) and certain other related neurodegenerative disorders are suspected.
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Natalizumab is a monoclonal antibody that is FDA-approved for the treatment of relapsing-remitting multiple sclerosis (MS). Among the available options to treat MS, it is one of the most effective.
