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Normal circulating plasma glucose concentration is maintained by a delicate constant balance between glucose utilization (i.e., glycolysis or storage as glycogen by various tissues) on one hand and glucose production on the other (i.e., glycogenolysis and gluconeogenesis induced in certain tissues, such as liver, muscle, renal parenchyma, and adipose tissue). During the late post-absorptive period or starvation, normal glucose concentration is maintained by facilitating glucose production while inhibiting glucose uptake.
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In response to several high-profile drug misadventures including the rofecoxib (Vioxx®) withdrawal from the market, the FDA's Center for Drug Evaluation and Research (CDER) asked the Institute of Medicine (IOM) to assess the drug safety system in the United States.
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Influenza can lead to death from pneumonia as well as exacerbations of underlying diseases of the heart, lungs, or other organ systems. More than 90% of deaths attributed to influenza and pneumonia occur in the elderly, and in the United States the mortality rate has been rising.
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Cardiovascular disease affects 25% of the U.S. population. It is responsible for more than 1 million deaths each year, which makes it the number one killer in the United States. Fifty percent of men and 64% of women who suffer from sudden cardiac death have no previous history or symptoms of heart disease.
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Can Calcium and Vitamin D Prevent Hip Fractures?; Treatment of Benign Prostatic Hyperplasia; Treatment of Osteoarthritis of the Knee; Refractory Asthma and TNFConnection?; FDA Actions
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The absorption of thyroxine is strongly influenced by stomach acidity, according to new study.
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This report begins with discussion of the most superficial lesions and progresses through the skin and soft tissue to the deeper and systemic disease processes.