Primary Care/Hospitalist
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Elagolix, Estradiol, and Norethindrone Acetate Capsules (Oriahnn)
Elagolix-EN should be prescribed to manage heavy menstrual bleeding associated with uterine leiomyomas (fibroids) in premenopausal women.
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Cloth Masks — Just for Looks?
How effective are homemade fabric masks many are using to protect others from COVID-19 transmission?
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MUCH Ado About WUCH
In a long-term, fixed-drug therapy of hypertension study, masked uncontrolled and white coat uncontrolled hypertension exhibited poor reproducibility over four years.
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Early Data on Remdesivir for Severe COVID-19: A Promising Start?
In this group of patients hospitalized with severe COVID-19, most of whom required invasive ventilation, 68% showed clinical improvement after treatment with remdesivir on a compassionate-use basis.
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Two Possible Mechanisms of Disease in COVID-19
COVID-19 infection may be associated with an increased risk of blood clotting and related thrombotic events, but there are insufficient data to support indiscriminately discontinuing medications that play a critical role in the management of chronic cardiovascular disease.
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Mystery Malaise: Discovering and Defining Burnout
Despite 40 years of research, definitions of key terms and measures regarding burnout are not yet standardized, hindering efforts to compare studies and to evaluate efficacy of treatment. Signs of burnout, such as emotional depletion and poor energy, overlap with mental health diagnosis (depression and anxiety, for example), leading some to wonder if burnout is a subtype of a mental health disorder.
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Examining Ginger for Ulcerative Colitis
For people with mild-to-moderate ulcerative colitis and who have symptoms and serum markers of inflammation and oxidation, some preliminary findings demonstrate both benefit and no difference when using 2 grams of ginger daily for 12 weeks vs. placebo.
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Cognitively Based Compassion Training for Parents Might Decrease Stress in Kids
The authors of this small, randomized, controlled trial found that Cognitively Based Compassion Training, a group-based technique taught to parents, was associated with decreased hair level of cortisol (a marker of decreased stress) in children whose parents completed this training.
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Exercise and Risk of Falls in Older Adults
The authors of this meta-analysis of 46 multinational randomized, controlled trials exploring the association between long-term exercise training and risk of serious outcomes in adults older than 60 years of age noted a statistically significant reduction in risk for some fall-related outcomes depending on the frequency and intensity of exercise training.