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In a longitudinal population-based study, metformin use was associated with an increased incidence of low thyroid-stimulating hormone (TSH) levels in patients with treated hypothyroidism.
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This study compared the metabolic cost for walking three different speeds in 30 adults at least 65 years of age, and found that those who ran on a regular basis expended less energy walking than the group that walked exclusively.
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Research about the human microbiome and the therapeutic effect of probiotics is changing fast. It can be difficult to know how to counsel our patients about this important topic.
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Large-scale observation data indicate an inverse association with circulating vitamin D levels and risk of death due to all causes, particularly cardiovascular and cancer-related death, while supplementation with vitamin D3 appears to reduce overall mortality among older adults.
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Individuals having peptic ulcer disease positive for Helicobacter pylori infection (diagnosed by endoscopy and biopsy with positive rapid urease test) were treated with either traditional quadruple therapy or quadruple therapy with licorice as a substitution for bismuth subsalicylate. After 4 weeks of treatment, eradication of H. pylori infection was comparable in both groups.
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Diversity of gut flora was significantly greater in highly trained athletes than in population controls, even after stratifying on the controls¡¯ body mass index. The athletes¡¯ level of exercise and diet may have been responsible, individually or jointly, for this phenomenon.
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Researchers from the Weizmann Institute of Science in Israel demonstrated that mice consuming non-caloric artificial sweeteners (NAS; e.g., saccharin, sucralose, and aspartame) in drinking water developed marked glucose intolerance compared to mice consuming only glucose or sucrose in drinking water.
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This article originally appeared in the November 29, 2014, issue of Internal Medicine Alert. It was edited by Stephen A. Brunton, MD, and peer reviewed by Gerald Roberts, MD. Dr. Brunton is Adjunct Clinical Professor, University of North Carolina, Chapel Hill, and Dr. Roberts is Senior Attending Physician, Long Island Jewish Medical Center, NS/LIJ Health Care System, New Hyde Park, NY.