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A meta-analysis was conducted of the incidence of side effects reported in randomized controlled trials of women taking phytoestrogens for the treatment of menopausal symptoms. Except for gastrointestinal side effects, women taking phytoestrogens were not at higher risk of side effects.
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Concerns over cell phones use and subsequent development of cancer, especially brain tumors, have occasionally dominated the news and helped create an entire business sector devoted to hands-free devices.
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A standardized extract of Tripterygium wilfordii Hook F root was compared with sulfasalazine therapy in subjects with active rheumatoid arthritis. After a 24-week intervention, those taking the botanical remedy experienced significantly greater progress both clinically and in laboratory assessments when compared with the sulfasalazine group, with improvements occurring rapidly. The findings are hampered somewhat by a significant dropout rate in both study groups.
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This single-group cohort before-and-after study of an intensive educational program for primary care physicians focusing on mindful communication and self-awareness demonstrated improvements in physician well-being and attitudes toward patient- centered care.
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The FDA has approved the first treatment for relapsed or refractory peripheral T-cell lymphoma. Pralatrexate, an inhibitor of dihydrofolate reductase, was granted accelerated approval by the FDA. It will be marketed by Allos Therapeutics as Folotyn™.
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The ECG shown above was obtained from a 72-year-old woman as a baseline. How would you interpret her ECG? How many blocked and early findings can you identify?
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The antiplatelet effect of clopidogrel is dependent upon its conversion and activation through the 2C19 pathway of the P450 system. Blockade of this pathway occurs because of genetics, in persons who do not have sufficiently active 2C19, and pharmacotherapies that specifically block 2C19. Proton pump inhibitors (PPIs), particularly omeprazole, are recognized to be 2C19 inhibitors. Is there reason for concern?
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Cholinesterase inhibitors place patients at risk for syncope, bradycardia, permanent pacemaker insertion, and hip fracture.
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Low levels of serum 25-hydroxyvitamin D [25(OH)D] in non-institutionalized older adults were associated with future increased mortality from all causes and from cardiovascular disease.
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Although health care providers have a major influence on their patients when they decide to undergo screening for prostate cancer, shared decision making often does not occur despite recommendations.
