Primary Care/Hospitalist
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Exercise Intervention for Improving Metabolic-Associated Fatty Liver Disease
Researchers assessed the histological appearance of liver biopsies from patients with metabolic-associated fatty liver disease (MAFLD) who completed 12 weeks of structured and supported aerobic exercise. Compared to biopsies from a nonexercising control group, the intervention arm demonstrated some reversal of histopathologic changes caused by MAFLD.
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Intracranial Plaque Rupture and Stroke
An MRI study of cerebral circulation in patients with embolic stroke of undetermined etiology showed evidence of atherosclerotic plaque in most patients.
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Ketogenic Diet Improves Cognition, Daily Function in Alzheimer’s Disease Patients
In a randomized, crossover trial, patients with Alzheimer’s disease on a ketogenic diet for 12 weeks demonstrated improved cognition, daily function, and quality of life.
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Transdiagnostic Cognitive Behavioral Therapy in Young Patients
This Danish randomized clinical trial compares a new form of cognitive behavioral therapy delivered in a community setting to “treatment as usual” for children and teens with emotional problems and shows advantages in multiple arenas, including parent-reported changes in child distress and impairment.
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Air Filters and Asthma
Asthmatic children showed improved small airway mechanics following indoor filtration of particulates (2.5 µm and greater) using high-efficiency particulate air filtration devices.
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Loneliness and Type 2 Diabetes Incidence
Loneliness appears to be an independent risk factor for type 2 diabetes, although further research to identify the causal relationship between loneliness and type 2 diabetes development is needed.
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2021 Update on Adult Vaccinations with a Focus on SARS-CoV-2/COVID-19
Vaccination in adults remains one of the most important means of preventing disease in vulnerable populations. Certain vaccines, such as influenza, tetanus/diphtheria/pertussis, and the new COVID-19 vaccine are recommended for all adults, while others are recommended in subsets of adults depending on age, comorbidities, and certain risk factors.
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AAP Revises Guidelines to Improve Treatment of Children with Disabilities
Group says pediatricians can be advocates for this population, which is more likely to be subjected to abuse and neglect.
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FDA Approves AI Tool to Help Detect Colon Cancer
Machine learning gives clinicians another tool while trying to detect troubling signs during routine screening.
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Dasiglucagon Injection (Zegalogue)
Dasiglucagon should be prescribed to treat severe hypoglycemia in pediatric and adult patients (≥ age 6 years).