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Primary Care/Hospitalist

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  • Vemurafenib Tablets (Zelboraf™)

    A kinase inhibitor for late-stage melanoma and its companion diagnostic test have been approved by the FDA.
  • ACE Inhibitors/ARBs for Aortic Stenosis?

    The authors conclude that this large observational study suggests ACEI or ARB therapy is associated with an improved survival and a lower risk of cardiovascular events in patients with aortic stenosis.
  • Why You Should Outsource Your Weight Loss Treatment

    Participation in Weight Watchers resulted in a greater weight loss over a year than did clinical intervention in a primary care office.
  • 15 to Life – Limited Exercise and Mortality Risk

    Data from this large observational trial with an average follow-up of over 8 years suggest that even 15 minutes a day of moderate-intensity exercise, such as taking a brisk walk, provides significant health benefits in terms of lowered mortality risks and life extension.
  • Just the Flax – Lignans and Postmenopausal Breast Cancer

    In a case-control study using a biomarker for lignan intake, women with breast cancer who had higher levels of the biomarker post-diagnosis had a reduced risk of mortality over a median follow-up period of 6 years compared to women with low levels of the biomarker.
  • Chinese Herbal Remedy for H1N1

    Thousands of Chinese used a compound called maxingshigan-yinqiaosan (MY) for treatment of flu symptoms during the 2009 H1N1 epidemic. MY is a concoction of 12 different herbs, including toasted Herba ephedra, as well as qinghao, gypsum fibrosum, and rhizoma.
  • Vitamin E and Prostate Cancer

    The SELECT Trial investigators report on nearly 10 years of follow-up of participants in a study of selenium and vitamin E and the risk of prostate cancer. A small but statistically significant increased risk of prostate cancer appears to be associated with taking vitamin E supplements. These results are in disagreement with others in the literature, and the authors present no plausible biological explanation for them. Nonetheless, the balance of evidence does not appear to support any recommendation that physicians advise their middle-aged and elderly patients to begin vitamin E supplementation for prostate cancer prevention.
  • Tea Totaling: Green Tea and Cholesterol

    A well-done meta-analysis showed that green tea, either as a beverage or as a supplement, could help lower total and LDL cholesterol levels in a statistically significant manner, but has no effect on HDL. The degree of clinical impact is debatable; what is not debatable is the poor quality of most studies on green tea and cholesterol.
  • Study shows issues with discharge instructions

    Patients and their caregivers sometimes have difficulty recalling details of their discharge instructions, a new study finds.
  • Personalize protection of patient health information to improve employee education

    A hospice can have encryption on all devices that include patient information as well as a full set of policies and procedures regarding the protection of patient information, but staff education is critical to ensure safety of data, says Brian Payne, chief executive officer at Winston-Salem Hospice and Palliative CareCenter in North Carolina.