Primary Care/Hospitalist
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New Analysis of COGENT Data Supports Proton Pump Inhibitor Benefit with Low and High Aspirin Doses
A dedicated analysis of the COGENT trial involving coronary artery disease patients on dual antiplatelet therapy shows comparable risks of gastrointestinal and cardiovascular events between low- and high-dose aspirin, and similar benefits of prophylactic proton pump inhibitor therapy. -
Communication Facilitators Potentially Can Improve Care for the Sickest ICU Patients
Highly trained communication facilitators who counseled families and met with physicians and nurses were shown to decrease symptoms of depression in family members at six months and decreased ICU length of stay without affecting mortality. -
Rivaroxaban in the Real World
A large Phase IV registry study shows that rivaroxaban is associated with a very low incidence of major bleeding, death, or stroke. Also, adherence to therapy was much higher than observed in other studies with vitamin K antagonists. -
Delaying Intubation in Severe Alcohol Withdrawal
Delaying intubation until aspiration or cardiopulmonary decompensation did not affect mortality but increased the incidence of pneumonia and length of stay. -
Integrative Treatment for Restless Legs Syndrome: What Does the Evidence Say?
Medical evidence supports the use of physical activity and iron supplementation (for those with low serum ferritin) in patients with restless legs syndrome.
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Integrative Approaches to Caring for Children with Autism
Selected treatments for autism spectrum disorder are reviewed and placed into one of four categories (ranging from recommend to avoid) with a goal of creating a practical blueprint for the medical practitioner.
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Improving Blood Pressure Through Enhanced Sleep
The use of a benzodiazepine hypnotic among hypertensive patients was associated with improvements in both sleep scores and blood pressure.
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Combination of Simvastatin Plus Vitamin D Offers New Hope for Migraine Prevention
A well-conducted, randomized, placebo-controlled trial has shown that the combination of simvastatin (20 mg twice daily) plus vitamin D3 (1,000 international units twice daily) is effective in the prevention of headaches in adults with episodic migraine.
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FDA Nutrition Facts Label Changes
The FDA recently announced changes to the nutrition facts panel required as a label on all foods.
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The Risks of a Low-salt Diet: A Meta-analysis
It indicates that people with or without hypertension are at increased risk of death or cardiovascular events when consuming low amounts of sodium.