Primary Care/Hospitalist
RSSArticles
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What Influences ICU Admission?
SYNOPSIS: There is widespread variability between hospitals in rates of ICU admission. High ICU utilization hospitals were more likely to use invasive procedures and incurred higher costs than low ICU utilization hospitals with no difference in mortality.
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Reported Beta-lactam Allergy Is Associated with More Adverse Events Among Inpatients
SYNOPSIS: A prospective cohort study from three hospitals determined that patients who did not receive a preferred beta-lactam antibiotic were at greater risk for an adverse event (adjusted odds ratio, 3.1; 95% confidence interval, 1.28-7.89) compared to controls without a beta-lactam allergy.
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Outcomes in Patients Treated with Therapeutic Hypothermia After In-hospital Cardiac Arrest
SYNOPSIS: Current guidelines recommend the use of therapeutic hypothermia in patients with in-hospital cardiac arrest, even though its efficacy has been demonstrated only in randomized trials after out-of-hospital cardiac arrest. This non-randomized, observational cohort study based on a large national registry found that the use of therapeutic hypothermia was associated with lower likelihood of survival and less favorable neurological outcome in patients successfully resuscitated after an in-hospital cardiac arrest.
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Clinical Briefs
In this section: treating refractory chronic pruritus, accelerating weight loss with technology, and lowering uric acid in gout patients.
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Eteplirsen Injection (Exondys 51)
Eteplirsen is indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients who present with confirmed mutation of the DMD gene that is amenable to exon 51 skipping.
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Warning: Reactivation of Hepatitis B Virus Coinfection During Treatment of Chronic Hepatitis C Virus Infection
Prior to initiation of hepatitis C virus treatment with direct-acting antivirals, patients should be screened for hepatitis B virus coinfection.
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Changing Gut Microbiota to Prevent Type 2 Diabetes
The long-term consumption of a healthy diet, such as the Mediterranean diet or low-fat/high complex carbohydrate diets, may exert a protective effect on the development of type 2 diabetes by changing the gut microbiota.
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Statins Associated with Lower Parkinson’s Risk in Diabetics
In approximately 50,000 individuals with Parkinson’s disease and diabetes, identified from a National Health Insurance database in Taiwan, statin use was dose-dependently associated with lower risk of Parkinson’s disease.
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Alzheimer’s Disease: What the Primary Care Physician Needs to Know
This article explores current medical approaches to Alzheimer’s dementia, the most common subtype of the known dementias or neurocognitive disorders. Preventive treatment is at the forefront of efforts to defeat this progressively impairing disorder; but to be effective, intervention must start well before symptoms begin. The role of the primary care provider in initiating vigorous and early preventive measures and applying appropriate pharmacologic and non-pharmacologic interventions at each stage of disease progression is reviewed and discussed.
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Why Do the Beats Keep Changing?
What clinical situation commonly is associated with arrhythmias such as the one shown in this figure?