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Primary Care/Hospitalist

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  • Cranberry Capsules Are Not Effective in Preventing Bacteriuria with Pyuria in Elderly Women in Nursing Homes

    A randomized, double-blind, placebo-controlled trial found that giving cranberry capsules to elderly women residing in nursing homes did not result in any significant benefits, including no reduction in symptomatic urinary tract infections.

  • Diastolic Blood Pressure Goals

    An analysis of the community-based ARIC study showed that low diastolic blood pressures were associated with higher baseline and subsequent troponin T levels and adverse cardiac events, but not stroke.

  • Male Hypogonadism

    Testosterone replacement therapy is a growing industry that deserves discussion between patients and their healthcare providers. Recently, many insights into new formulations, advertising, and potential risks have heightened the controversy surrounding low testosterone syndrome, appropriate diagnosis, and risks and benefits of testosterone supplementation. A plethora of non-regulated supplements termed “testosterone boosters” are being marketed directly to the public without adequate assessment. Therefore, it is important for healthcare providers to be familiar with how to conduct and interpret diagnostic tests as well as with appropriate use of TRT as established by various medical organizations, including the Endocrine Society. This review will discuss the definitions, pathophysiology, causes, clinical manifestations, appropriate diagnostic testing procedures, and the role of testosterone supplementation with currently available formulations, with special attention to efficacy and adverse effects in hypogonadism in men.

  • An Alternating QRS with AV Block?

    There is no 12-lead ECG on this patient, which means that our assessment of QRS morphology is limited to this single right-sided MCL-1 monitoring lead.

  • Clinical Briefs

    In this section: connecting asthma to obesity; finding the right treatment for uncomplicated gastroesophageal reflux disease; and better blood pressure control.

  • Bezlotoxumab Injection (Zinplava)

    Bezlotoxumab neutralizes the effect of toxin B and reduces the rate of recurrence of C. difficile infection.

  • Is Yoga Effective for Treating Asthma?

    Although the data on yoga in asthma are only of moderate quality, they suggest that yoga may improve quality of life and asthma symptoms.

  • What Influences ICU Admission?

    High ICU utilization hospitals were more likely to use invasive procedures and incurred higher costs than low ICU utilization hospitals with no difference in mortality.

  • Is Anxiety a Risk Factor for Cardiovascular Disease?

    Anxiety disorders are associated with an elevated risk of a range of different cardiovascular events including stroke, coronary heart disease, heart failure, and cardiovascular deaths, but it is unclear whether these disorders are causal in nature.

  • Just Two HPV Shots Recommended for Younger Teens

    The CDC now recommends that 11- to 12-year-olds receive two doses of HPV vaccine at least six months apart, rather than the previously recommended three doses.