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On March 21, 2014, two new antibiotics with activity against methicillin-resistant Staphylococcus aureus (MRSA) each received unanimous recommendations from FDA Advisory Committees for approval for treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by Gram-positive organisms.
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This study comes from the legacy Multicenter AIDS Cohort Study (MACS) of almost 7000 men who have sex with men, both HIV-infected and non-HIV, for 3 decades.
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In a neonatal intensive care unit in Arizona, five infants and ten health care providers were found to have pertussis during a two month period.
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As this issue went to press a second case of MERS was identified in Florida even as the Indiana case was being discharged in good condition. Here is what was known at press time.
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In a sample of New York City immigrants with dilated cardiomyopathy the point prevalence of infection with Trypanosoma cruzi was found to be 13%.
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A Cochrane review questions the value of osletamivir and zanamivir in the treatment of influenza virus infections – but the CDC and IDSA disagree.
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The first U.S. case of MERS-CoV infection diagnosed in the U.S. has been identified in an individual traveling from Saudi Arabia.
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Since the introduction of the vaccine against H. influenzae, there has been a significant decrease in the number of children presenting with epiglottitis. Although there is little evidence that the disease has increased in adults, clearly the percentage of cases in adults compared to children has increased. Further, there is greater recognition of milder cases with direct visualization and imaging.
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The immunogenicity of trivalent influenza vaccine is attenuated by the administration of A(H1N1)pdm09 4 months before, an effect partially overcome by the presence of an adjuvant in the former.
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In a single academic medical center, changing from a strategy of prior authorization to prospective audit with feedback led to significantly increased total antibiotic use and use of agents with a broad spectrum of gram-negative activity.