Pharmacology Watch
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Federal Agencies, States Move Swiftly to Combat Opioid Overdose Epidemic
CDC issues new pain management guidelines; White House, states bring own ideas to the table.
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FDA Actions
In this section: Senate confirms new FDA commissioner, and the FDA approves brivaracetam as adjunctive treatment for partial onset seizures.
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Report: Prescriptions for Hydrocodone-containing Combination Drugs Drop
The switch of hydrocodone-containing combination drugs from Schedule III to the more restrictive Schedule II in October 2014 significantly reduced the number of prescriptions filled for these drugs, according to a new study.
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A Secondary Prevention Against Cardiovascular Events?
A recent study found that in patients without diabetes but with insulin resistance along with a history of ischemic stroke or TIA, pioglitazone reduced the risk of stroke or myocardial infarction compared to placebo.
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Treating Gout with Oral Steroids
New research indicates prednisolone is an effective and safe first-line option for the treatment of acute gout.
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More Doubt About ‘Female Viagra’
Flibanserin, on average, resulted in a one-half additional satisfying sexual event per month while significantly raising the risk of dizziness, somnolence, nausea, and fatigue.
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Long-term Aspirin Use Reduces Risk of Cancer
Regular aspirin use could prevent 33 colorectal cancers per 100,000 person years among those who had not undergone lower endoscopy and 18 colorectal cancers per 100,000 person years in those who had undergone screening.
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FDA Actions
The FDA has approved a new fixed-dose combination oral, once-daily pill to treat hepatitis C genotypes 1 and 4.
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Time to Limit Proton Pump Inhibitors?
A new study suggests the commonly used drugs may be associated with chronic kidney disease.
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Promising Treatment Not Widely Available
Among adults with recurrent or refractory Clostridium difficile infection, the use of frozen compared with fresh fecal microbiota transplantation did not result in worse proportion of clinical resolution of diarrhea.