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  • MTHFR Clinical Considerations: A Review

    With the introduction of genetic testing that is increasingly affordable, more patients are approaching their health care providers about such testing or with results from their direct-to-consumer genetic tests. Research findings linking MTHFR gene polymorphisms and disease risk have been conflicting. This has led to challenges as far as interpreting such data.
  • De-SELECT? Vitamin E, Selenium, and Prostate Cancer

    Results of the SELECT trial, a large randomized, placebo-controlled, double-blind trial designed to help determine whether selenium, vitamin E, or both could safely prevent prostate cancer in middle-aged and older men, were not to be published for another four years. Interim analyses, however, revealed no benefit from therapy, and even some potential health concerns.
  • Old and New Treatments for Irritable Bowel Syndrome: Effective or Not?

    This article was a systematic review and meta-analysis of high-quality randomized controlled trials determining the effect of fiber, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome, and demonstrating superiority of the three examined therapeutic modalities as compared to placebo.
  • Statins, Sterols, and Stanols

    Margarines containing plant sterols and stanols can be an effective long-term therapeutic intervention to aid with cholesterol lowering in people already on a stable statin regimen.
  • Glucosamine Sulfate for Osteoarthritis

    Osteoarthritis is the most common form of arthritis and a leading cause of disability in the United States.
  • Carnitine Shows Promise Against Risk Factor for Cardiovascular Disease

    Carnitine supplementation produced beneficial changes in endothelial function as measured by flow-mediated dilation (FMD) after a high-fat meal. No significant differences were found for other biomarkers of inflammation and oxidative stress.
  • What's That Herb Again ... ? Ginkgo for Dementia

    A well-regarded, standardized extract of Ginkgo biloba does not appear to help prevent development of dementia in seniors with baseline normal or mildly impaired cognitive function. Whether use of ginkgo earlier in life has a primary preventive effect on development of dementia remains to be determined.
  • News Briefs: Overall Use of CAM by U.S. Adults Remains Steady, but Some Therapy Use Varies

    Approximately 38% of adults in the united states aged 18 years and older and nearly 12% of U.S. children aged 17 years and younger use some form of complementary and alternative medicine (CAM), according to a nationwide government survey conducted in 2007.
  • Yogurt and You? Probiotics and Infant Atopic Dermatitis

    Probiotics are often thought of as concentrated yogurt capsules, most useful for the prevention or treatment of antibiotic-induced diarrhea. Recent evidence, though, is starting to point to a much greater use for the provision of "good bacteria" to the gastrointestinal tract.
  • What's That Herb Again...? Ginkgo for Dementia

    A well-regarded, standardized extract of Ginkgo biloba does not appear to help prevent development of dementia in seniors with baseline normal or mildly impaired cognitive function. Whether use of ginkgo earlier in life has a primary preventive effect on development of dementia remains to be determined.