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Margarines containing plant sterols and stanols can be an effective long-term therapeutic intervention to aid with cholesterol lowering in people already on a stable statin regimen.
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This article was a systematic review and meta-analysis of high-quality randomized controlled trials determining the effect of fiber, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome, and demonstrating superiority of the three examined therapeutic modalities as compared to placebo.
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Results of the SELECT trial, a large randomized, placebo-controlled, double-blind trial designed to help determine whether selenium, vitamin E, or both could safely prevent prostate cancer in middle-aged and older men, were not to be published for another four years. Interim analyses, however, revealed no benefit from therapy, and even some potential health concerns.
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Massage is one of the most commonly used non-pharmacological interventions for managing cancer pain.
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Healthy middle-aged men and women with normal LDL-cholesterol levels and elevated levels of the inflammatory biomarker high-sensitivity C-reactive protein (hsCRP) show significant decreases in clinical cardiovascular events when treated with rosuvastatin vs placebo.
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A well-regarded, standardized extract of Ginkgo biloba does not appear to help prevent development of dementia in seniors with baseline normal or mildly impaired cognitive function. Whether use of ginkgo earlier in life has a primary preventive effect on development of dementia remains to be determined.
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Probiotics are often thought of as concentrated yogurt capsules, most useful for the prevention or treatment of antibiotic-induced diarrhea. Recent evidence, though, is starting to point to a much greater use for the provision of "good bacteria" to the gastrointestinal tract.
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This study compared the metabolic cost for walking three different speeds in 30 adults at least 65 years of age, and found that those who ran on a regular basis expended less energy walking than the group that walked exclusively.
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Research about the human microbiome and the therapeutic effect of probiotics is changing fast. It can be difficult to know how to counsel our patients about this important topic.
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Large-scale observation data indicate an inverse association with circulating vitamin D levels and risk of death due to all causes, particularly cardiovascular and cancer-related death, while supplementation with vitamin D3 appears to reduce overall mortality among older adults.
