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In this issue: Rivaroxaban may be dabigatran's first competitor; a new way to measure non-adherence to medication therapy; FDA Actions.
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In 1854, london was rocked by a cholera epidemic that killed approximately 10,000 people. Using what are now considered classical epidemiological methods, Dr. John Snow traced the source of at least 500 of the infections to a single water pump at Broad Street, validating his theory that cholera was a water-borne disease 29 years before the etiologic agent was discovered by Robert Koch; removing the pump handle stopped the outbreak in that area.
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I was asked earlier this week to see a patient with candidemia. The patient had severe cirrhosis and had previously had placement of a transjugular intrahepatic portosystemic shunt (TIPS) for control of complications of portal hypertension.
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In this study, 2,499 hiv-seronegative men or transgender females who have sex with men (MSM) were randomized to daily TDF/FTC vs. placebo in a multicenter, controlled trial with clinical sites in North America, Latin America, Thailand, and Africa.
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Group B streptococcal (GBS) disease is the leading cause of early-onset neonatal sepsis (within the first week of life) in the United States.
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The Centers for Disease Control and Prevention guidelines to prevent infection with carbapenem-resistant pathogens include the following recommendations.
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Robert Rapp, PharmD, professor of pharmacy at the University of Kentucky Chandler Medical Center, is an outspoken advocate for antibiotic stewardship to preserve the efficacy of our remaining antibiotics against rising drug resistance.
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The continuing global emergence of multidrug resistant gram negative pathogens bugs that are virtually impervious to all antibiotics and can transfer resistance mechanisms between species means infection prevention is more critical than ever during every patient encounter.
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Threatening to spread to North America after originating in hospitals in India, the pan-resistant New Delhi metallo-beta-lactamase (NDM-1) enzyme has been linked to a fatal infection in Canada.
