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A new randomized trial using either a calcium channel blocker or an ACE inhibitor to lower systolic blood pressure to the low 120s prevented cardiac events in patients with coronary artery disease compared with systolic blood pressures around 130.
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Sleep restriction (to 4 hours a night) resulted in increased appetite, increased cortisol levels, lowered TSH levels, worsened glucose tolerance and lower heart rate variability compared with sleep extension (to 12 hours a night) in young healthy volunteers.
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Measures that increase adiponectin levels might be valuable targets for decreasing the risk of atherosclerosis present in patients with diabetes.
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Eradication of H. pylori in a large outpatient general practice setting seemed to protect against the subsequent onset of gastroesophageal reflux disease (GERD), and there was evidence that eradication of H. pylori neither improved nor worsened pre-existing GERD symptoms.
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The British government will soon allow over-the-counter (OTC) sales of Mercks simvastatin (Zocor), marking the first time any country has allowed the OTC sale of a statin.
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Prevention of Disabling and Fatal Strokes by Successful Carotid Endarterectomy in Patients without Recent Neurological Symptoms; Cox-2 Inhibitors vs Nonselective NSAIDs and CHF Outcomes in Elderly Patients; Interventions for the Prevention of Falls in Older Adults
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The first nonabsorbable, gastrointestinal-selective antibiotic has been approved for the treatment of travelers diarrhea caused by noninvasive strains of Escherichia coli.
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In a prospective, randomized trial, primary excision of colorectal carcinomas by laparoscopic surgery was compared with laparotomy. Disease recurrence and 5-year survival were not significantly different in the 2 groups. Operative time was greater for those receiving laparoscopic approach but post-operative recovery and hospital stays were shorter.
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Infection rates in low-risk human bites are exceedingly low. Antibiotic treatment may not be necessary for these patients.
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