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Rewind to 2007. A large HIV vaccine clinical trial sponsored by Merck & Co. is shuttered after an interim analysis concluded that the vaccine did not prevent infection. Fast forward to today.
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Strategies to determine treatment of acute coronary syndromes need to take gender into account.
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Lifestyle changes plus red yeast rice and fish oil resulted in similar beneficial effects on LDL cholesterol as moderate-dose statin therapy in patients meeting criteria for drug therapy for high LDL cholesterol.
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Optimizing medical and lifestyle change therapy rather than performing PCI is appropriate as the initial management strategy for most patients with known CAD who do not have unstable or disabling symptoms.
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A randomized controlled trial in the Netherlands showed that oral prednisolone and naproxen were equivalent in the treatment of acute gout with no difference in side effects.
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Using blood pressure, BUN, serum sodium, and presence of peripheral arterial disease as predictors of mortality in heart failure patients, 67% who had 3 or more factors died within 6 months and would qualify for the Medicare hospice benefit.
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There are no disease-modifying pharmacotherapies for COPD. That is, although bronchodilators, anticholinergic agents, and inhaled corticosteroids improve FEV1 and reduce symptoms, decline in pulmonary function continues unabated and lung function returns promptly to pretreatment status once medication is stopped.
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Between March, 2005 and June 2007, 1622 consecutive patient charts at Temple University Hospital were reviewed to determine whether prophylactic antibiotics were used appropriately with regard to antibiotic choice, timing of administration, and postoperative cessation of antibiotics.