Obstetrics/Gynecology
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The Association Between SSRIs and Congenital Anomalies
In this synthesis involving 15 meta-analytic studies, four studies demonstrated an association between paroxetine use during pregnancy and increased risk of major congenital anomalies (relative risk [RR], 1.18 [95% confidence interval (CI), 1.05, 1.32] to 1.29 [95% CI, 1.11-1.49]). For all selective serotonin reuptake inhibitors (SSRIs), the RR for major anomalies (1.10 [95% CI, 1.03, 1.16] to 1.27 [95% CI, 1.09, 1.47]) and cardiac defects (1.06 [95% CI, 0.94, 1.18] to 1.36 [95% CI, 0.61, 3.04]) were increased. This meta-analysis suggests an increased risk of cardiac and major anomalies with SSRI use, but the results should be interpreted with caution, since all included studies were meta-analyses of retrospective cohort studies.
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Management of Heavy Menstrual Bleeding: Levonorgestrel-Releasing Intrauterine System vs. Endometrial Ablation
In this multicenter, randomized, noninferiority trial among patients aged 34 years and older with heavy menstrual bleeding, the levonorgestrel-releasing intrauterine system did not meet the noninferiority threshold when compared to endometrial ablation for mean blood loss at 24 months following intervention. Both interventions did lead to large decreases in blood loss and comparable satisfaction and quality-of-life scores.
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New Program for LGBTQ Youth Is Designed to Reduce Unintended Pregnancies
A researcher created a new program for LGBTQ youth based on the idea that this population experiences more difficulty accessing reproductive healthcare, partly because of problems related to their choice of pronouns and names. The program addresses which contraceptives and intrauterine devices transgender boys can use, and which are effective and do not interfere with their hormone treatment. -
Study Finds No Differences in Pregnancy Plans Between Young Black and White Women
Black and white young women share similar desires to avoid pregnancy and similar pregnancy plans, but Black women were much less likely to be pronatal, advocating for a higher birth rate, than were white women, new research revealed. The unintended pregnancy rate is 2.5 times higher for Black women than for white women, which raises questions about why this difference occurs. -
Research Shows Low-Sensitivity Pregnancy Test Works Well After Medication Abortion
New research shows using a low-sensitivity pregnancy test after a medication abortion is both accurate and safe. The 1,000 mIU/mL low-sensitivity pregnancy test or the five-level multilevel pregnancy test can be used safely without a visit to a provider’s office or clinic. -
New Oral Contraceptive Holds Promise of Few or No Blood Clots, Other Adverse Effects
Recent research has shown that a new combined oral contraceptive has high efficacy, cycle control, and safety, even among a diverse American population that included women with a body mass index of 35 kg/m2. The medication contains estetrol (a novel estrogen) and drospirenone. -
Pandemic Stress, Burnout Contribute to Nursing Pipeline Shortage
Stress, burnout, turnover, and retirement have contributed to obstacles in the student-to-nursing workforce pipeline. Nursing students and other healthcare professionals have experienced anxiety during the COVID-19 pandemic, research shows. This affected both nursing and medical students as well as nurses working in any healthcare settings. -
Research Shows Reproductive Health Nurses Needed in 2020s
The United States will soon need millions more nurses than are currently working in healthcare. But employers, including family planning centers and OB/GYN offices, likely will have a difficult time finding nurses. The American Nurses Association predicts more registered nurse jobs will be available through 2022 than any other profession. A half-million nurses are expected to retire by the end of 2022. -
Is a Vacuum-Induced Device Effective for Control of Postpartum Hemorrhage?
In this multicenter study across 12 centers in the United States, a vacuum-induced intrauterine device successfully treated 94% of participants who experienced a postpartum hemorrhage with a median time of three minutes to control of bleeding.
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Anticholinergic Use for Three Months or More Increases Dementia Risk
There is a significant increase in dementia risk associated with the use of anticholinergic medications for three months or longer.