Obstetrics/Gynecology
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Oral vs. IV Iron for the Treatment of Iron-Deficiency Anemia in Pregnant Women
Compared to oral iron, intravenous iron reduced maternal anemia at delivery (40% vs. 85%, P = 0.039), and rates of maternal hemoglobin < 10 g/dL were lower with intravenous iron compared to oral iron (10% vs. 54%, P = 0.029). Rates of mild to moderate adverse events were similar between the two groups, and no severe adverse reactions were noted with intravenous iron.
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The Pseudogestational Sac of Ectopic Pregnancy: Does it Really Matter?
In this retrospective cohort study of 1,236 women, the rate (2.2%) of ectopic pregnancy was rare among women with a fluid collection (or pseudosac) in the uterus. The size of the fluid collection was not predictive of ectopic pregnancy. The presence of an intrauterine fluid collection decreased the risk of ectopic pregnancy (adjusted relative risk, 0.09; 95% confidence interval, 0.05-0.19) after adjusting for age and the presence of bleeding.
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Is the Timing of Interval Postpartum Insertion of Intrauterine Device Associated with the Frequency of Complications?
Having an intrauterine device (IUD) inserted at four to eight weeks postpartum was associated with higher frequency of uterine perforation, but not higher frequency of expulsion, compared to IUD insertion at nine to 36 weeks postpartum. Overall, perforation and expulsion rates were low.
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Clindamycin Vaginal Gel 2% (Xaciato)
Clindamycin gel can be prescribed to treat bacterial vaginosis in women age 12 years and older.
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U.S. Chlamydia Rates Continue to Climb
The chlamydia infection rate has been rising unabated. While rates of some STIs have fluctuated over the past 40 to 80 years, chlamydia rates have increased progressively since the first reporting data became available in 1984. -
Herpes Vaccine Could Be Available by 2030
Early efforts to produce a protein-based vaccine for herpes failed. But a new mRNA approach has outperformed the efficacy of the past vaccines in preclinical trials and is expected to be introduced in clinical trials in the second half of 2022, investigators say. This new approach for a prophylactic genital herpes vaccine showed great promise in early studies.
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STI Rates Increasing, but Efficient Testing Can Help
Incidence rates of many sexually transmitted infections (STIs) have increased in the years leading up to the COVID-19 pandemic. There is evidence that STIs have continued to rise during the pandemic, according to the results of a new study. -
Accessing Hormonal Contraception by Pharmacy Prescriptions
A stopgap step to increasing access to hormonal birth control is to expand prescribing authority to pharmacists. Compared to other clinical settings, pharmacies can be easier for people to access, given their wide distribution across the country and their extended hours of operation. -
Researchers Highlight Isolation, Stigma of Abortion Providers in the South
Abortion providers in the South face many challenges, including being outed online, fired from hospitals, and ostracized in professional and social circles, according to the results of a recent study. -
Disrupted Contraceptive Care Hurt Disadvantaged Patients the Most
The COVID-19 pandemic affected most women seeking contraceptive care — but those who already are disadvantaged by structural inequities were hit the hardest. The problem worsened as the pandemic continued. The pandemic made reproductive health access disparities worse, creating economic hardship for many women and disproportionately affecting Black, indigenous, and people of color. Recently, researchers found that people were less happy with their ability to access contraceptive care in January 2021 than in July 2020.