A medical research unit in the United Kingdom analyzed 18 different strategies for managing patients with suspected deep vein thrombosis (DVT). Using systematic review, meta-analysis and cost effectiveness analysis, they settled on an algorithm based on clinical risk.
HCV may persist and replicate in the liver and PBMCs of healthy, anti-HCV antibody-positive, serum HCV RNA-negative patients who have persistently normal ALT levels. These patients should be followed up, because they have an ongoing viral infection.
Antibiotics may improve acute purulent rhinitis at the cost of gastrointestinal upset and rash.
Tight glucose control has been shown to provide improved outcomes in both Type 1 and Type 2 diabetes (DM2).
Functional dyspepsia cannot reliably be diagnosed using symptoms alone. Esomeprazole therapy is not effective vs placebo in an 8-week study of endoscopy-negative patients with histories thought to be diagnostic of FD.
Warfarin remains superior to antiplatelet agents for stroke prevention in patients with AF.
The FDA has approved the first, one tablet, once-daily, three-drug combination for the treatment of HIV-1 infections.
Three days of amoxicillin is as effective as five for mild-to-moderately severe community-acquired pneumonia.
