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Efficacy and Safety of Benazepril for Advanced Chronic Renal Insufficiency; Prognostic Value of Thyroid Hormone Levels in Acute MI: Just an Epiphenomenon?; Nonsteroidal Anti-inflammatory Drugs and the Risk of Actinic Keratoses and Squamous Cell Cancers of the Skin
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The FDA has approved the first of a new class of agents, the vaptans. Conivaptan, the first arginine vasopressin receptor antagonist, is approved for the management of serious sodium/water imbalance. It will be marketed by Astellas Pharma US, Inc as Vaprisol®.
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This case series and prospective observational study describe propylene glycol toxicity in patients receiving IV benzodiazepines. The authors estimate the incidence of this important but unrecognized complication to be 19%.
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Illnesses produced by vascular diseases are far and away the most common cause of death in the developed world and, amazingly enough, will become the leading cause of death even in the developing world by 2020.1 Identifying individuals at increased risk of coronary artery heart disease (CHD) is critical in preventing CHD and, in 2002, the Adult Treatment Panel III (ATP III)2 reaffirmed its previous position by concluding that low-density lipoprotein cholesterol (LDL-C) would remain the cornerstone of lipid management.
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The use of a steroid ointment following a 20-minute soak may relieve chronic skin conditions.
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Do Antidepressants Increase Risk of Suicide?; Can Viagra Improve Heart
Function?; A Dramatic Increase of Clostridium difficile; FDA Actions
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In a clinical trial conducted in Mexico City, 162 women with systemic lupus erythematosus were randomized to treatment with 1 of 3 contraceptive methods: estrogen-progestin oral contraceptives, oral progestin-only, or a copper IUD. Disease activity remained equally mild and stable over 1 year in all 3 groups.
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The standard approach to adjuvant therapy in women with advanced ovarian cancer is intravenous platinum-based chemotherapy, usually in combination with a taxane. Since the disease is largely characterized by a disseminated intraperitoneal spread pattern, investigators have been interested as whether the disease may respond to therapy administered in the same route.