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Itopride, a D2 dopamine agonist with anticholinesterase effects, was marginally superior to placebo in 'functional dyspepsia.'
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Visual hallucinations, extrapyramidal motor signs, and visuoconstructional impairments at time of presentation are strongly suggestive of a diagnosis of dementia with Lewy bodies.
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A novel T-cell inhibitor has been approved for the treatment of rheumatoid arthritis. Abatacept is the first selective modulator of a costimulatory signal involved in T-cell activation (costimulatory blocker).
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Optimal surgical cytoreduction is a recognized staple of initial advanced ovarian cancer care. However, within the spectrum of patients who undergo this surgery are those in whom complete resection is either impossible or unwarranted in the face of certain unacceptable morbidity.
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Jick and colleagues, epidemiologists at Boston University School of Medicine, performed a case-control study of nonfatal venous thrombosis using information derived from a very large database that records prescriptions and diagnoses longitudinally in managed health care plans.
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The association between exogenous estrogen use and endometrial cancer development has been well documented. Nonetheless, the hazard of estrogen replacement therapy in women with a personal history of endometrial cancer has not been well studied and, despite anecdotal evidence of its safety, is largely discouraged among clinicians.
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Treatment of Benign Prostatic Hyperplasia; Treatment of Osteoarthritis of the Knee; Refractory Asthma and TNFConnection?; FDA Actions
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The Womens Health Initiative (WHI) conducted a randomized trial of Calcium and Vitamin D supplementation.1 The 36,282 postmenopausal women were part of the WHI clinical trials involving postmenopausal hormone therapy or dietary modification. The average follow-up was 7 years; 37% of the women were age 50 to 59, 45.5% were 60 to 59, and 17.5% were 70 to 79.
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In November the authors of the now famous FASTER trial, which was initially focused on the use of nuchal translucency (NT) in the first trimester, published one of many spin-off reports.
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