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The Womens Health Initiative (WHI) conducted a randomized trial of Calcium and Vitamin D supplementation.1 The 36,282 postmenopausal women were part of the WHI clinical trials involving postmenopausal hormone therapy or dietary modification. The average follow-up was 7 years; 37% of the women were age 50 to 59, 45.5% were 60 to 59, and 17.5% were 70 to 79.
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Treatment of Benign Prostatic Hyperplasia; Treatment of Osteoarthritis of the Knee; Refractory Asthma and TNFConnection?; FDA Actions
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The association between exogenous estrogen use and endometrial cancer development has been well documented. Nonetheless, the hazard of estrogen replacement therapy in women with a personal history of endometrial cancer has not been well studied and, despite anecdotal evidence of its safety, is largely discouraged among clinicians.
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Jick and colleagues, epidemiologists at Boston University School of Medicine, performed a case-control study of nonfatal venous thrombosis using information derived from a very large database that records prescriptions and diagnoses longitudinally in managed health care plans.
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Optimal surgical cytoreduction is a recognized staple of initial advanced ovarian cancer care. However, within the spectrum of patients who undergo this surgery are those in whom complete resection is either impossible or unwarranted in the face of certain unacceptable morbidity.
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Scientists are preparing to take the next step in the search for a spray-on contraceptive, with a Phase II trial scheduled for the second half of 2006.
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While the decision to make emergency contraception (EC) available over the counter remains in a holding pattern at the Food and Drug Administration, advocates are moving on the state level to allow pharmacists to dispense EC without a physicians prescription under certain conditions.
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While no microbicide has yet moved from the research pipeline to the pharmacy shelf, progress is going forward on several fronts to develop female-controlled physical and chemical barrier methods to prevent HIV and other sexually transmitted diseases (STDs).
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The next patient at your STD (sexually transmitted diseases) clinic is a young man with a mucoid/purulent anal discharge and a lymph node enlargement in the groin area.