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Bonny and colleagues report the effect of depot medroxyprogesterone on weight changes in obese and nonobese adolescent girls. This was a prospective study of 450 adolescents, aged 12 to 18 years.
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Clarkson and colleagues report the results of a lower-dose estrogen trial in a monkey model of coronary atherosclerosis. The animals were fed an atherogenic diet for 10 months, calculated to induce atherosclerosis comparable to that observed in early postmenopausal women.
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Psoriasis sufferers may face an increased risk of having a heart attack, a new study suggests. The risk appears to be most pronounced among younger patients with more severe forms of the disease.
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In response to several high-profile drug misadventures including the rofecoxib (Vioxx®) withdrawal from the market, the FDA's Center for Drug Evaluation and Research (CDER) asked the Institute of Medicine (IOM) to assess the drug safety system in the United States.
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Influenza can lead to death from pneumonia as well as exacerbations of underlying diseases of the heart, lungs, or other organ systems. More than 90% of deaths attributed to influenza and pneumonia occur in the elderly, and in the United States the mortality rate has been rising.
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Wait and see prescriptions (WASP) is a new concept for the treatment of otitis media in children.
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Impaired Fasting Glucose (IFG) and impaired glucose tolerance (IGT) appear to be the steps directly preceding the development of overt diabetes.
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A new agent has been approved for the treatment of the neovascular (wet) form of age-related macular degeneration (AMD).