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Obstetrics/Gynecology

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Articles

  • Gaps Remain in Alcohol Use Screening Among Pregnant Patients

    Despite the known benefits, it appears some clinicians still do not counsel women to avoid alcohol during pregnancy.

  • Probiotics and Iron Intake in Pregnancy

    In a randomized controlled trial, a significantly smaller decrease in serum ferritin was observed in pregnant women with the intake of a Lactiplantibacillus plantarum 299v supplement containing a low dose of iron, folic acid, and ascorbic acid than in the placebo group.

  • Provider Perceptions of Neonatal Survival for Fetuses Born at 22 Weeks of Gestation

    Prognostic differences exist among neonatal and obstetric care providers when neonates are delivered at 22 weeks of gestation. However, there are no statistically significant differences in the gestational age at which providers recommend active treatment or antenatal corticosteroids.

  • New Treatments for Uterine Fibroids

    In this prospective, open-label, single-arm trial of 149 individuals with heavy menstrual bleeding and uterine leiomyomas, daily relugolix combination therapy (relugolix 40 mg, estradiol 1 mg, and norethindrone acetate 0.5 mg) resulted in a mean menstrual blood loss reduction of 90%, and 70% of the participants achieved amenorrhea by the end of the 52-week period. Similar results were found for other arms of the trial among women who crossed over from placebo and relugolix-only therapy to relugolix combination therapy.

  • #IUD on TikTok: An Analysis of Intrauterine Device-Related Content on Social Media

    The top 100 videos on the social media platform TikTok were compiled and systematically analyzed for user demographics and video content. More videos had a negative tone, particularly those conveying patient experiences related to pain and informed consent.

  • Current and Future Options for Male Contraception

    Following the landmark Dobbs v. Jackson Women’s Health Organization decision that ended the constitutional right to abortion in the United States, the importance of contraception has grown. This article summarizes the existing male contraceptive options and reviews the status of future ones.

  • Ibrexafungerp for Vulvovaginal Candidiasis

    A randomized clinical trial compared one day of oral ibrexafungerp with placebo for female patients with vulvovaginal candidiasis (VVC). It found ibrexafungerp to be safe and effective, with mild diarrhea the most common adverse event. Ibrexafungerp differs mechanistically from azoles and appears to be a promising new treatment for VVC.

  • Effectiveness of an Online e-Health Program in Ameliorating Postpartum Depression

    This study demonstrated that combined use of universal depression screening and MomMoodBooster2, a cognitive behavioral therapy-based e-health program, were effective tools for treating women with depression in the perinatal period.

  • A Simple Intervention to Reduce Surgical Site Infections?

    This multicenter, cluster randomized trial in Benin, Ghana, India, Mexico, Nigeria, Rwanda, and South Africa evaluated the effect of changing sterile gloves and instruments at the time of abdominal wound closure on surgical site infection (SSI) rates among adults and children undergoing both elective and emergent surgery. The SSI rate in the intervention group among 5,789 patients was 16% compared to 18.9% in the control group of 6,768 patients (adjusted risk ratio, 0.87; 95% confidence interval, 0.79-0.95).

  • Ethical Concerns if Researchers Examine Opioid Use During Pregnancy

    Researchers who are examining opioid use in pregnant patients face significant ethical complexities when designing study protocols. A group of ethicists examined these issues and concluded an embedded approach to address ethical implications of these studies is needed.