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There has been a steady rise of labor inductions in the United States during the last decade, a trend that has gone hand-in-hand with the cesarean section rate.
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To evaluate the effectiveness of mammography as a screening test, the authors used the Surveillance, Epidemiology, and End Results (SEER) database to examine trends from 1976 through 2008 in the incidence of early-stage breast cancer (ductal carcinoma in situ and localized disease) and late-stage breast cancer (regional and distant disease) among women 40 years of age or older in the United States.
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Data were accessed from the nurses health study, which enrolled 121,700 U.S. female registered nurses who were 30-55 years old at the outset in 1976. Every 2 years, participants provided information about their lifestyle, medical history, and illnesses via mailed questionnaires.
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In this issue: Zolpidem and risk of falls; AVR and anticoagulation; statins in cancer patients; and FDA actions.
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The authors performed a nested case-control study using data from the Rochester Epidemiology Project which conducts population-based studies of the residents of Olmsted County, Minnesota.
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In this issue: Lorcaserin for weight loss; statins and fatigue; treatment-resistant gonorrhea; hydrocodone classification changes; USPSTF recommendations; and FDA actions.
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Apropos of the recent emphasis on discouraging elective deliveries prior to 39 weeks, a group from Cincinnati embarked on a study to determine whether steroids had any neonatal benefit in patients delivering between 34 and 39 weeks who had immature amniotic fluid lung profiles.
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The authors performed a prospective cohort study, the contraceptive CHOICE Project, in which women in the St. Louis, Missouri, region received a reversible contraceptive method of their choice for up to 3 years at no cost.
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To provide guidance to clinicians on the use of hormone replacement therapy, the authors conducted a systematic review of the randomized, placebo-controlled trials of menopausal hormone therapy published in English since 2002 that assessed primary prevention of chronic conditions.