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The epidemiologic investigators of the Womens Health Initiative (WHI) report a comparison of cardiovascular events in the observational arm with 53,054 women and the clinical trial arm with 16,608 women.
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The incidence of twins is now about 1 in 40 pregnancies, up from the 1 in 80 figure over a decade ago. Infertility treatments are almost exclusively responsible for this doubling effect.
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Development and evaluation of novel agents to treat patients with ovarian cancer is a continuous (particularly for recurrent ovarian cancer patients) as well as curative therapy in this setting has yet to be identified.
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I missed this article when it first emerged. however, during a recent perinatal conference in California, Dr. Michael Nageotte cited it in an excellent lecture on breeches. Since the report could have an impact in current practice, I am reviewing it in this issue.
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A surprising study recently surfaced in the British Medical Journal. A randomized trial was designed to determine if giving a standard maternal dose of steroids (two injections of 12 mg of betamethasone separated by 24 hours) would decrease the incidence of respiratory distress syndrome (RDS) in infants whose mothers were to have elective Cesarean sections.
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E3N is a French prospective study of cancer risk factorsEtude Epidémiologique de femmes de la Mutuelle Générale de lEduction National. The study population, after exclusions, consists of 54,548 women born between 1925 and 1950, and all belong to a health insurance program that primarily covers teachers.
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Population-based ovarian cancer screening programs have been difficult to recommend and implement because poor sensitivity and positive predictive value characteristics accompany expensive and inefficient testing methodology and triage algorithms.
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Ogburn and colleagues report on their experience with adnexal torsion at one university medical center from 1990 to 2001. A chart review identified 68 patients in whom laparoscopic management was accomplished 32% of the time (n = 22) and ovarian conservation in 21% (n = 14).
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Endometrial cancer is the most common gynecologic malignancy and is usually characterized by limited disease at presentation. Among the number of known prognostic factors, grade of disease is one frequently used to triage patients for formal surgical staging.
