Silverman and colleagues reported the prevalence of depression in a cross-sectional subset of 3798 women in 6 English-speaking countries, who participated in the Multiple Outcomes of Raloxifene Evaluation (MORE) trial.
Neoadjuvant Chemotherapy (NACT) for ovarian cancer refers specifically to the administration of cytotoxic therapy ahead of a planned surgical resection usually for primary therapy.
Case and her co-authors performed a blinded and prospective evaluation of the accuracy of frozen section analysis in a cohort of 60 patients undergoing a surgical staging attempt. Their institutional policy was to formally stage all patients regardless of the uterine tumor characteristics.
Black and colleagues reported the results of an extension of the alendronate Fracture Intervention Trial (FIT) in which the participants were randomized after 5 years of treatment either to another 5 years of treatment or placebo.
This is a prospective, randomized, multi-centered study from Sweden in which the psychological well-being of 125 women scheduled for hysterectomy was evaluated for up to 6 months post-operative. Of those enrolled, 119 completed the study with 56 undergoing abdominal hysterectomy and 63 having a laparoscopic hysterectomy.
Citalopram Useful for Depression in CDA Patients; When to Stop Anticoagulation Before Surgery?; Drug Warnings: Ranibizumab and Bevacizumab, Growth Hormone Treatment, More Harm Than Good, FDA Actions
In a recent paper, Walker and McDowell contacted 1200 patients having had this procedure since 1996 at either the Royal Surrey County Hospital or the London clinic. One hundred eight women had tried to become pregnant and 33 succeeded at least once. In total, the authors had data on 56 completed pregnancies.
Women with pathogenic mutations in BRCA1 or BRCA2 are known to be at substantially higher lifetime risk for ovarian and breast cancer than the general population. The degree to which reproductive factors affect this risk has been estimated but is limited by studies of small sample size or faulty methodology.
These Iranian investigators randomized treatment of 108 patients with unruptured ectopic pregnancy to either a single dose protocol or a multiple dose protocol. The single dose regimen was successful in 48/54 cases (88.9%), while 92.6% (50/54) patients responded to the multiple-dose regimen.
