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Germline mutations in BRCA1 or BRCA2 associated with the Hereditary Breast/Ovarian Cancer syndrome have an increased lifetime risk for breast (up to 85%) and ovarian (up to 46% BRCA1, up to 27% BRCA2) cancer.
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A team of epidemiologists from several institutions in the US performed a case-control study of the association between oral contraceptive use and lobular and ductal breast cancer occurring in young women (under age 44).
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Wilkinson and colleagues from the University of Texas in Galveston analyzed information from the Surveillance, Epidemiology, and End Results (SEER) databank linked to Medicare claims.
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In a study of 82 patients with primary dysmenorrhea who had been randomized to undergoing either LUNA or LUNA + PN, the two groups had comparable results (69% improved in the LUNA group; 73% in the LUNA+PN group) at up to 12 months of follow-up.
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In this issue: Updated Immunization Guidelines from the CDC; Do antivirals have a role in the treatment of Bell's palsy? Topiramate is a promising treatment for alcohol dependence; and FDA Actions.
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WISDOM was a multicenter, randomized, placebo-controlled clinical trial of postmenopausal hormone therapy that began recruitment in 1999 in the U.K. and in 2000 in Australia and New Zealand. The trial was prematurely cancelled in 2002 after the initial publication of results in the Women's Health Initiative (WHI).
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It is one thing to be empathetic, but it is something quite different to be able to convey empathy to the patient.
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Zometa and hip fractures; Merck HIV Vaccine Ineffective in Clinical Trial; Thimerosal and Mercury Exposure; FDA Actions
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The title says it all in this randomized controlled trial by Sullivan and colleagues "Administration of cefazolin prior to skin incision is superior to cefazolin at cord clamping in preventing post-cesarean infectious morbidity."
