OB/GYN Clinical Alert
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CIN2 Is More Likely to Progress if HPV 16 Is Present
This study examined rates of cervical intraepithelial neoplasia grade 2 (CIN2) regression and progression among women ages 25-30 years and found that regression rates varied by human papillomavirus (HPV) genotype: 51% regression and 47% progression in HPV 16 infections compared to 83% regression and 16% progression for infections with other HPV types.
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Diagnosis of Obstructive Sleep Apnea During Pregnancy
Obstructive sleep apnea is associated with several adverse maternal and fetal outcomes.
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Retrospective Cohort Analysis of Perinatal Outcomes Following Bariatric Surgery
In a retrospective study of a racially and ethnically diverse cohort in 2012-2018, patients with a live birth after bariatric surgery had a lower risk of preeclampsia, gestational diabetes or impaired fasting glucose, and having a large-for-gestational-age infant — but a higher risk of having a small-for-gestational-age infant — relative to matched controls who did not have bariatric surgery before their live birth.
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Opioid Use Disorders During Pregnancy
Currently, the United States faces an enormous opioid crisis, with opioid use disorder (OUD) being the leading cause of morbidity and mortality in some states. The number of pregnant people with OUD increased from 1.5 cases per 1,000 hospital deliveries to 6.5 cases per 1,000 hospital deliveries in the United States between 1999 and 2014, a more than four-fold rise. Proper identification and management of pregnant and postpartum people with OUD is crucial.
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The Efficacy of Prenatal Patients Using a Mindfulness App
This randomized trial conducted early in the pandemic with women from an obstetric and gynecologic practice found use of a mobile app promoting mindfulness practice (such as meditation) was associated with a decrease in perceived stress, self-reported anxiety and depression, and sleep disturbance in the intervention group.
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Do Anti-Müllerian Hormone Levels Decline More Rapidly After Hysterectomy with Ovarian Conservation?
In this multi-site, community-based study, anti-Müllerian hormone levels did not decline more rapidly among patients who underwent hysterectomy with ovarian conservation compared to patients who experienced natural menopause.
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Is Vaginal Carbon Dioxide Laser an Effective Treatment for the Genitourinary Syndrome of Menopause?
In this double-blinded, randomized controlled trial, fractional carbon dioxide vaginal laser was no better than sham laser in improving Female Sexual Function Index scores among 72 breast cancer survivors on aromatase inhibitors over a six-month period.
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Controlling Blood Pressure During Pregnancy Could Lower Dementia Risk
Investigators found an association between high blood pressure during pregnancy and a higher likelihood of developing dementia later in life.
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Breast Milk Feeding Among Women Who Had Been Infected with SARS-CoV-2 During Their Pregnancy
Both breast milk feeding during the postpartum hospital stay and infant rooming-in during this time were common in the five states studied from March 29 to Dec. 31, 2020, among the births that occurred to women who had a laboratory-confirmed case of SARS-CoV-2 during their pregnancy.
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Identifying High-Risk Cancer Patients Through Appropriate Screening
Less than 20% of average-risk women receive guideline-adherent cervical cancer screening, and guideline-adherent screening was highest for primary human papillomavirus testing.