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The above study involved a detailed analysis of data obtained in the observational arm of the Women's Health Initiative. As a rationale, the authors note that obesity is a well-established risk factor for breast cancer.
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The stars were aligned when four papers appeared in two obstetrical journals within a month of each other dealing with the optimal time in gestation to deliver.
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A recent study in patients with fibroids has correlated the size, location, and number of fibroids with the rate of preterm birth, postpartum hemorrhage, need for cesarean section, and fetal size findings that can be useful in counseling patients with fibroids.
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A large prospective cohort study of perineal talc use demonstrated no increased risk of ovarian cancer overall or within any histological subtype. In addition, no association with talc application method was observed.
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According to this pharmacokinetic study, the cyclic use of 20 mcg ethinyl estradiol oral contraceptives is problematic for obese women. Ovarian activity was better suppressed with continuous use (omitting the hormone-free interval) of the same dose oral contraceptive or increasing to a higher dose 30 mcg ethinyl estradiol oral contraceptive
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Polycystic ovarian syndrome patients with normospermic partners undergoing ovulation induction with letrozole had a higher live birth rate and no increase in adverse outcomes than women who received clomiphene citrate.
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In this pooled analysis of more than 7700 ovarian cancer patients and nearly 12,000 controls, low-dose aspirin and high-dose non-aspirin NSAID use was associated with a risk reduction for invasive epithelial ovarian cancer of 20-34% relative to non-users. Acetaminophen use was not associated with a risk reduction, irrespective of dose or frequency.
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In a large Norwegian population-based cohort study, women with a history of unilateral oophorectomy experienced a slightly earlier onset of menopause compared to women with both ovaries, but this finding does not suggest a clinically important effect.
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A retrospective cohort study of 519 women diagnosed with polycystic ovary syndrome demonstrates that black adolescents and reproductive-aged adults have a higher risk for metabolic syndrome and cardiovascular disease compared to their white counterparts.