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Primary insomnia unrelated to depression is a common and debilitating condition that heightens the risk for accidents, cardiovascular disease, and other long-term health conditions. About 10-25% of adults older than age 54 years report insomnia defined as subjective complaints of poor sleep accompanied by impairment in daytime functioning.
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Pockaj and colleagues from the Mayo Clinic reported the results of a double-blind, randomized, cross-over clinical trial to study the efficacy of black cohosh for the treatment of menopausal hot flushes.
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Bevacizumab is a fully humanized, monoclonal antibody targeting the proangiogenic factor, vascular endothelial growth factor or VEGF.
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Treating Chronic Primary Insomnia; New Breakthrough in Smoking Cessation?; FDA Actions
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In this case-control study, the authors matched 235 graduates of 3 medical schools who were disciplined by their respective medical boards between 1990 and 2003 with 469 control physicians who were matched based on graduation year and medical school.
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One of the most recognized risk factors for the development of endometrial cancer is obesity. However, recent studies have suggested that this factor alone cannot fully account for all the risk associated with obesity.
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In this New Zealand investigation, 257 premenopausal women undergoing hysterectomy were prospectively compared to 259 cohorts who did not have a hysterectomy.
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Twenty-three patients are reported with osteonecrosis of the mandible or maxilla associated with bisphosphonate treatment.
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The STAR Trial (Tamoxifen and Raloxifene); FDA Actions
