OB/GYN Clinical Alert
RSSArticles
-
Oral Contraception and Obesity
This study was a re-analysis of drospirenone 4 mg Phase III efficacy trials comparing 590 non-obese and 325 obese patients who showed equivalent pregnancy rates with Pearl Indices of 3.0 (95% confidence interval [CI], 1.3 to 5.8) and 2.9 (95% CI, 0.8 to 7.3), respectively.
-
Magnesium Sulfate for Neuroprotection
Magnesium sulfate did not improve neurological function and child survival at 2 years of age in women at risk of imminent preterm birth treated between 30 and 34 weeks of gestation.
-
How Did the COVID-19 Pandemic Affect Permanent Contraception Procedures?
A national review of inpatient permanent contraception procedures between Jan. 1, 2019, and Dec. 31, 2020, demonstrated that the rate of procedures decreased in 2020 compared with 2019, with the steepest monthly decline (14.5%) being between February and April 2020, the first wave of the COVID-19 pandemic.
-
Rh Sensitization Following Induced Abortion
In this multicenter, observational, prospective cohort study, flow cytometry was used to detect circulating fetal red blood cells (fRBCs) in maternal blood among 506 participants before and after induced abortion up to 12 weeks’ gestation. Only three participants had elevated fRBCs at baseline, and only one of these had elevated fRBC counts following the abortion, which indicates that first trimester abortion is not a risk factor for Rh sensitization.
-
The Association Between BMI and Diagnosis of Endometrial Intraepithelial Neoplasia at an Early Age
In premenopausal patients, there was a linear association between increasing body mass index and decreased age at the time of endometrial intraepithelial neoplasia diagnosis.
-
Multicomponent Intervention for Early Detection and Treatment of Postpartum Hemorrhage: E-MOTIVE
This international, parallel, cluster-randomized trial assigned 80 secondary-level hospitals in four African countries to evaluate a multicomponent intervention for early detection and treatment of postpartum hemorrhage (PPH) vs. usual care following a vaginal birth. The intervention group had 60% less severe PPH cases (> 1 L blood loss) than the usual care cohort.
-
Unscheduled Bleeding with the Contraceptive Implant: Is There Any Intervention that Works?
In this randomized controlled trial of 54 patients with frequent or prolonged bleeding or spotting on the etonogestrel contraceptive implant, curcumin (the active ingredient in turmeric) was no better than placebo at controlling the total number of bleeding or spotting days during the 30-day study period.
-
Implications of Reproductive Carrier Screening During Pregnancy
About 1 in 40 females who underwent reproductive carrier screening were found to be carriers for a disease that could cause maternal symptoms during pregnancy. Healthcare providers should be aware of the potential for complications among carriers of genetic conditions during pregnancy and the best practices for handling such cases.
-
What Every OB/GYN Should Know About Cervical Cancer Prevention
This narrative review summarizes the steps of human papillomavirus (HPV)-mediated cervical carcinogenesis and uses this to explain current guidelines for HPV vaccination, cervical cancer screening, and management of abnormal results.
-
Integrating Reproductive History Could Help Postmenopausal Women’s Long-Term Brain Health
Researchers observed patients with higher cumulative estrogen exposure throughout their life may be at lower risk of developing cerebral small vessel disease.