OB/GYN Clinical Alert
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Who Needs an Endometrial Biopsy?
In this retrospective cohort study of premenopausal women with abnormal uterine bleeding, obesity, as opposed to age, was the most significant predictor of complex hyperplasia or cancer on endometrial biopsy.
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Did You Remember to Take Your Hormone Replacement? The Treatment May Not Help
Women randomized to receive postmenopausal oral estradiol therapy did not show improved memory, executive function, or global cognition, and timing of initiation of hormonal treatment did not affect the outcome.
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Extending Life of LARCs: More Years for Your Implant
An international study found that continued use of an etonogestrel contraceptive implant for up to five years, two years longer than the current labeling approval, did not increase the risk of pregnancy.
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When to Start Progestin-only Contraceptives After Medical Abortion
In this randomized, controlled trial, provision of depot medroxyprogesterone acetate on the same day as mifepristone for medical abortion decreased efficacy a small amount and had no effect on repeat pregnancy at six months. Whether this is clinically relevant will depend on individual patient counseling and the woman’s desire for convenient contraceptive coverage.
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The Effect of Major Depression on Quality of Life After Surgery for Stress Urinary Incontinence
Women with major depression undergoing surgical treatment for stress urinary incontinence have worse condition-specific quality of life than non-depressed women. Postoperatively, depressed and non-depressed women have similar incontinence severity and quality of life.
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The Best Medical Treatment for Endometriosis? The Debate Continues
In a “before and after study,” the proportion of satisfied and very satisfied women did not change from the “before” period, during which women with endometriosis were treated with norethindrone acetate, to the “after” period during treatment with dienogest.
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Should We Still Be Performing Annual Pelvic Exams?
<>The recent draft guidance from the United States Preventive Services Task Force (USPSTF) on the utility of periodic screening with the pelvic examination has inspired renewed debate on this topic. -
Glucose Screening: The Meaning of a Single Abnormal Value in a 3-hour Glucose Tolerance Test
A recent 25-study meta-analysis has shown that patients having only one elevation in a three-hour glucose tolerance test have similar maternal and fetal outcomes as patients diagnosed to have bona fide gestational diabetes.
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HPV Testing: An Approach Whose Time Has Come?
A recent study found that genotyping for human papillomavirus 16/18 is a reasonable approach to help calculate the risk of progression to CIN3 or worse.
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Hormonal Contraception: A Risk Factor for Depression?
A population-based study suggests that hormonal contraception increases the risk of treatment for depression, but bias provides a more likely explanation for the association.