OB/GYN Clinical Alert
RSSArticles
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Predicting Recurrence After Pelvic Organ Prolapse Surgery
SYNOPSIS: Prediction models can provide helpful information regarding the risk of recurrence after prolapse surgery.
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Ultrasound vs. MRI in Diagnosis of Placenta Accreta
The authors of this two-center study found that magnetic resonance is not superior to ultrasound in diagnostic accuracy for placenta accreta spectrum disorders, and its usefulness is tempered particularly by a tendency to falsely upgrade the stage of severity.
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Welcome New Board Member
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Should Two-Dose Methotrexate Be the Standard of Care for Ectopic Pregnancy?
In this meta-analysis, the two-dose methotrexate treatment protocol was associated with higher odds of treatment success and a shorter treatment period compared to the single-dose protocol.
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Ripples From Original WHI Study Results Continue: Is This Appropriate?
Recommendations for menopausal hormone therapy were widely publicized and adopted following the original publication of the results of the Women’s Health Initiative and affected both initiation and continuation of estrogen therapy through at least 2013.
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Perimenopausal Depression
OB/GYNs strive to screen women for perinatal depression both in pregnancy and postpartum. Although depression frequently affects reproductive-age women, it is common in women throughout the lifespan. This article discusses depression in perimenopausal women.
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Brexanolone for Postpartum Depression: Promising, but Will It Deliver?
In two double-blind, randomized, placebo-controlled, Phase III trials of brexanolone, a new medicine for postpartum depression, researchers found a significant reduction in symptoms at 60 hours of infusion compared to placebo.
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Pregnancy Temporarily Increases Breast Cancer Risk: Parallels to Hormonal Contraception?
In a pooled analysis of prospective studies, researchers found an increased risk of breast cancer among parous women that persists for more than 20 years after childbirth. Breastfeeding did not modify this pattern.
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Low-Dose Aspirin and Preterm Birth
SYNOPSIS: A reanalysis of an earlier randomized clinical trial to assess the ability of low-dose aspirin to prevent preeclampsia has shown that the drug diminishes the risk of spontaneously delivering prior to 34 weeks by about half.
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Does Treatment of Bacterial Vaginosis Prevent Spontaneous Preterm Birth?
In this randomized, controlled trial from France, screening for and treatment of bacterial vaginosis in pregnant women at low risk for preterm birth with oral clindamycin or placebo did not reduce the rate of spontaneous preterm birth between 16 and 36 weeks.