OB/GYN Clinical Alert
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Adverse Perinatal Outcomes Related to Intrahepatic Cholestasis of Pregnancy
While a diagnosis of intrahepatic cholestasis of pregnancy is associated with an increased risk for stillbirth, preterm birth, and neonatal respiratory issues, consensus on management within the obstetrics community has not been reached.
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Are We Doing Too Many Unnecessary Pelvic Exams and Pap Tests in Young Women?
In this cross-sectional national survey, the authors estimated that 23% of women aged 15 to 20 years had received a bimanual pelvic exam, of which half (54%) were deemed potentially unnecessary, and 19% of the population received a Pap test, of which 72% were potentially unnecessary.
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Knowledge of Pelvic Floor Disorders Among Pregnant and Postpartum Women
Pregnant and postpartum patients lack knowledge about urinary incontinence and prolapse.
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Baby-Friendly Policies May Be Ineffective in Improving Breastfeeding Outcomes in the United States
Data analysis from the 2018 Centers for Disease Control and Prevention Breastfeeding Report Card failed to show improvements in breastfeeding outcomes in Baby-Friendly facilities over statewide breastfeeding initiation programs.
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CNS Agents Emerge as Frontrunners in FDA-Approved Treatments for Low Libido in Women
Low libido is the most common sexual complaint, affecting up to 38.7% of women, with up to 12.3% also reporting significant distress associated with this condition. In the past five years, for the first time in history, there are two Food and Drug Administration-approved medications specifically for treating hypoactive sexual desire disorder in women. Of note, both medications are central nervous system agents.
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Estrogen Replacement: Is Long Duration of Therapy Good for the Brain?
Longer lifetime exposure to endogenous estrogen and menopausal estrogen replacement were associated with better cognitive status in older adult women. Women who initiated estrogen therapy early (within five years of the onset of menopause) showed higher cognitive test scores than those who started later.
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Tenaculum Placement Techniques and Effect on Pain
In this randomized controlled trial, there was no difference in pain score with tenaculum placement between the slow method of application and coughing with application (median pain score 44 vs. 32, P = 0.16).
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What Are the Roles of the Combined Oral Contraceptive Pill and Metformin in the Management of Polycystic Ovary Syndrome?
This systematic review documents the effectiveness of combined oral contraceptive pills in treating hyperandrogenism and irregular menses, and of metformin in addressing the metabolic disturbances in women with polycystic ovary syndrome.
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The Affordable Care Act: Progress in Reducing the Rate of Unintended Pregnancy
Data from the latest release of the National Survey of Family Growth supports that the contraception coverage mandate of the Affordable Care Act has resulted in a decrease in the incidence of unintended pregnancy, particularly among women with government coverage.
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PARP Inhibitors: An Adjunct to Initial Standard Treatment for Advanced Ovarian Cancer Patients
The PRIMA study is a randomized, double-blind, multi-institutional, international phase 3 trial testing the PARP inhibitor niraparib against placebo after first-line standard treatment with platinum-based chemotherapy for newly diagnosed ovarian cancer.