OB/GYN Clinical Alert
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Gabapentin for Pain Reduction During First-Trimester Uterine Aspiration
In this randomized, double-blind, placebo-controlled trial, 600 mg of oral gabapentin administered one to two hours pre-procedure did not reduce pain during or after first-trimester surgical abortion.
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Menopausal Hormonal Therapy and Breast Cancer Risk: Are Old Data Relevant to Today’s Practice?
An individual-participant meta-analysis of prospective studies found menopausal hormone therapy associated with an elevation in the risk of breast cancer, with the highest risks associated with daily combined therapy.
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Maternal Sleep Position and Pregnancy Outcomes
Questions regarding sleep position safety are often posed for any OB/GYN or midwife practicing obstetrics.
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Recommendations for the Use of Testosterone Therapy in Women: A Global Consensus Statement
Exogenous testosterone is currently indicated only for women with documented hypoactive sexual desire disorder/dysfunction.
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Consensus Position Statement on the Use of Testosterone in Women
A task force of representatives from leading international societies issued guidance for appropriate prescribing of testosterone in women.
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Intrauterine Device Use and Ovarian Cancer Risk
In this systematic review, the odds ratio of ever-use of an intrauterine device and incident ovarian cancer was 0.68 (95% CI 0.62-0.75).
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Sedentary Behavior, Physical Activity, and Nighttime Urinary Symptoms
Sedentary behavior is associated with more severe symptoms of nocturia and nocturnal enuresis in women with urinary incontinence.
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Molecular Analysis of Endometrial Cancer Corresponds With Outcomes in Young Women
SYNOPSIS: In this retrospective cohort study, researchers studied the prognosis and outcomes for young women with endometrial cancer and compared them according to tumor molecular classification.
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Association Between Self-Reported Prenatal Cannabis Use and Maternal, Perinatal, and Neonatal Outcomes
Cannabis use during pregnancy has become commonplace in states and countries (Canada) where it has been legalized for medical and/or recreational use. The authors of this study attempted to determine whether associations exist between self-reported prenatal cannabis use and maternal and perinatal outcomes.
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Does Vaginal Estradiol Reduce Pain With Sexual Activity?
A post-hoc analysis of data from a 12-week randomized study that compared vaginal estradiol to vaginal moisturizers found no increase in sexual frequency or decrease in pain associated with either treatment, compared to placebo.