OB/GYN Clinical Alert
RSSArticles
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HIV Management During Pregnancy
Human immunodeficiency virus (HIV) infection during pregnancy carries a significant burden to healthcare systems, and continues to be of significant public health concern.
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The Cost-Effectiveness of HPV Vaccination for Adults Aged 30 to 45 Years
This study evaluated the cost-effectiveness of extending the upper age limit of human papillomavirus (HPV) vaccination to age 30 to 45 years using two independent HPV microsimulation models and found that vaccinating in this age group was not cost-effective.
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Are Modern Intrauterine Devices Associated with Infertility?
In this prospective cohort study of 461 women, there was no association between intrauterine device use and time to conception (hazard ratio, 1.25; 95% confidence interval, 0.99-1.58). However, past Mycoplasma genitalium infection was found to be associated with longer times to conception and lower conception rates by 12 months (68% vs. 80%, P = 0.02).
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The Levonorgestrel IUD Is Similarly Effective as the Copper IUD for Emergency Contraception
In this randomized, noninferiority trial among patients seeking emergency contraception after at least one episode of unprotected intercourse within five days of presentation, the levonorgestrel 52-mg intrauterine device (IUD) was noninferior to the copper T30A IUD at preventing pregnancy one month after IUD insertion. Adverse events between the two groups were similar.
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Does Prescription of Contraception During the Postpartum Hospitalization Affect Postpartum Visit Adherence?
In this retrospective cohort study of 1,015 women at one institution, there was no association between type of contraceptive prescribed immediately postpartum and attendance at the postpartum visit.
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Is it Safe to Discharge Patients Without an Opioid Prescription After Gynecologic Surgery?
In this quality improvement initiative study, patients undergoing scheduled gynecologic abdominal surgery via both minimally invasive and open routes were able to be discharged safely without a prescription of opioids without significant increases in postoperative calls about pain or the need for filling opioid prescriptions after discharge.
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Loop Electrosurgical Excision Procedure of the Cervix: Which Is the Best Method of Anesthesia?
In this randomized controlled trial comparing local anesthesia and general anesthesia for loop electrosurgical excision procedure of the cervix, there was no difference in patient satisfaction. However, women in the local anesthesia group had significantly smaller cone volumes and less blood loss than those in the general anesthesia group.
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A Prospective Look at the Course of Untreated ADHD in Pregnancy Gains Attention
Twenty-five women with perinatal attention-deficit hyperactivity disorder were followed prospectively during pregnancy for changes in anxiety, depression, perceived stress, and functional impairment. Statistically significant differences in mood and functional impairment in the family domain were found in those who discontinued their psychostimulant.
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Oral Progestogens for Prevention of Miscarriage
In this double-blind, randomized clinical trial, 406 pregnant women were randomized to dydrogesterone or placebo. There were no statistically significant differences in the primary outcome (miscarriage before 20 weeks of gestation; relative risk, 0.897; 95% confidence interval, 0.548-1.467; P = 0.772), which occurred in 12.8% and 14.3% in the dydrogesterone and placebo arms, respectively. The use of dydrogesterone in women with threatened miscarriage for the prevention of early pregnancy loss in the first trimester failed to decrease the miscarriage rate or increase the live birth rate.
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Is HPV Testing Superior to Pap Testing Alone in Women at Risk of Cervical Cancer?
In this registry-based screening study of women in Catalonia, Spain, a negative human papillomavirus (HPV) and cytology co-test at baseline was associated with a cumulative incidence of cervical precancer of 0.4% at five years and 1.3% at nine years, compared to 27% among women with abnormal HPV testing at baseline.